B
Basanth Babu Eedara
Researcher at University of Otago
Publications - 24
Citations - 505
Basanth Babu Eedara is an academic researcher from University of Otago. The author has contributed to research in topics: Dissolution testing & Solubility. The author has an hindex of 11, co-authored 21 publications receiving 362 citations.
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Journal ArticleDOI
Solid self-nanoemulsifying drug delivery system (S-SNEDDS) of darunavir for improved dissolution and oral bioavailability: In vitro and in vivo evaluation.
Spandana Inugala,Basanth Babu Eedara,Sharath Sunkavalli,Rajeshri Dhurke,Prabhakar Kandadi,Raju Jukanti,Suresh Bandari +6 more
TL;DR: Investigation of solid self-nanoemulsifying drug delivery system (S-SNEDDS) composed of Capmul MCM C8, Tween 80 and Transcutol P found presence of drug in non-crystalline amorphous state without any significant interaction of drug with the components of S- SNEDDS.
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Improved oral bioavailability of fexofenadine hydrochloride using lipid surfactants: ex vivo, in situ and in vivo studies.
TL;DR: The ex vivo permeation studies conducted using intestinal gut sac technique, resulted in reduced efflux of the drug by inhibiting intestinal P-glycoprotein from the dispersions, and Fourier transform infrared spectroscopy revealed the compatibility of drug with carriers.
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Development of isradipine loaded self-nano emulsifying powders for improved oral delivery: in vitro and in vivo evaluation.
TL;DR: Results signify the improved oral delivery of isradipine from developed SNEP from developed self-nano emulsifying powders.
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Phospholipid-based pyrazinamide spray-dried inhalable powders for treating tuberculosis.
TL;DR: Solid state characterization confirmed that the α-polymorphic crystalline pyrazinamide transformed into the γ- polymorphic form during spray-drying, and further evaluation of the developed inhalation powders is necessary to determine their therapeutic potential for treating pulmonary tuberculosis.
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The influence of surface active l-leucine and 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) in the improvement of aerosolization of pyrazinamide and moxifloxacin co-spray dried powders.
TL;DR: The differences in the aerosolization behaviours of the pyrazinamide and moxifloxacin spray dried powders with and without excipients was a combination of difference in the surface morphology and surface composition.