Bastian Hoesel

TL;DR: An overview of the most relevant modes of crosstalk and cooperativity between NF-κB and other signaling molecules during inflammation and cancer is provided.

TL;DR: The role of NF-κB signaling in cell types within the vasculature and the circulation that are involved in thrombo-inflammatory processes is focused on, as it is critically involved in pathophysiological processes as it induces both inflammatory and thrombotic responses.

TL;DR: In this paper, the molecular and biochemical mechanisms of ursodeoxycholic acid (UDCA) in modulating the cross-talk between liver and visceral white adipose tissue (vWAT) regarding BA and cholesterol metabolism and fatty acid/lipid partitioning in morbidly obese NAFLD patients were explored.

TL;DR: Genetic and pharmacologic experimental approaches in vitro, as well as in vivo autoimmunity models, provide convincing evidence that PI3K/PTEN-regulated extracellular Arginase I acts as a paracrine regulator of inflammation and immunity.

TL;DR: An enhanced gene regulatory network for mice in a simulation program that models the growing PSM by many virtual cells and integrates WNT3A and FGF8 gradient formation, periodic gene expression and Delta/Notch signaling is presented.