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Carolin Lackner
Researcher at Medical University of Graz
Publications - 107
Citations - 5243
Carolin Lackner is an academic researcher from Medical University of Graz. The author has contributed to research in topics: Cirrhosis & Liver disease. The author has an hindex of 34, co-authored 98 publications receiving 4192 citations. Previous affiliations of Carolin Lackner include University of Bern & University of Graz.
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Journal ArticleDOI
Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing
Ellen Heitzer,Martina Auer,Christin Gasch,Martin Pichler,Peter Ulz,Eva M. Hoffmann,Sigurd Lax,Julie Waldispuehl-Geigl,Oliver Mauermann,Carolin Lackner,Gerald Höfler,Florian Eisner,Heinz Sill,Hellmut Samonigg,Klaus Pantel,Sabine Riethdorf,Thomas Bauernhofer,Jochen B. Geigl,Michael R. Speicher +18 more
TL;DR: This study paves the way to use CTCs as a liquid biopsy in patients with cancer, providing more effective options to monitor tumor genomes that are prone to change during progression, treatment, and relapse.
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Comparison and validation of simple noninvasive tests for prediction of fibrosis in chronic hepatitis C.
Carolin Lackner,Gerd Struber,Bernadette Liegl,Sebastian Leibl,Petra Ofner,Csilla Bankuti,Bernd Bauer,Rudolf E. Stauber +7 more
TL;DR: Simple fibrosis tests may render liver biopsy unnecessary only in a minority of patients with chronic HCV, and improved serum fibrosis markers with greater sensitivity for severe fibrosis or cirrhosis are needed.
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Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity
Michaela Mueller,Anders Thorell,Thierry Claudel,Pooja Jha,Pooja Jha,Harald Koefeler,Carolin Lackner,Bastian Hoesel,Guenter Fauler,Tatjana Stojakovic,Curt Einarsson,Hanns-Ulrich Marschall,Michael Trauner +12 more
TL;DR: In this paper, the molecular and biochemical mechanisms of ursodeoxycholic acid (UDCA) in modulating the cross-talk between liver and visceral white adipose tissue (vWAT) regarding BA and cholesterol metabolism and fatty acid/lipid partitioning in morbidly obese NAFLD patients were explored.
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Ballooned hepatocytes in steatohepatitis: the value of keratin immunohistochemistry for diagnosis
Carolin Lackner,Margit Gogg-Kamerer,Kurt Zatloukal,Conny Stumptner,Elizabeth M. Brunt,Helmut Denk +5 more
TL;DR: Loss of keratin 8/18 immunostaining can serve as an objective marker of a specific type of ballooning degeneration of hepatocytes in cases of acute hepatitis, giant cell hepatitis, chronic hepatitis B, or autoimmune hepatitis.
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Effects of n-3 fish oil on metabolic and histological parameters in NASH: A double-blind, randomized, placebo-controlled trial
Curtis K. Argo,James T. Patrie,Carolin Lackner,Thomas D. Henry,Eduard E. de Lange,Arthur Weltman,Neeral L. Shah,Abdullah M. S. Al-Osaimi,Patcharin Pramoonjago,Saumya Jayakumar,Saumya Jayakumar,Lukas Binder,Winsor D. Simmons-Egolf,Sandra G. Burks,Yongde Bao,Ann Gill Taylor,Jessica E. Rodríguez,Stephen H. Caldwell +17 more
TL;DR: N-3 PUFAs at 3000 mg/day for one year did not lead to an improvement in the primary outcome of histological activity in NASH patients, but n-3 led to reduced liver fat by multiple measures.