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Beatriz S. Stolf

Researcher at University of São Paulo

Publications -  37
Citations -  1056

Beatriz S. Stolf is an academic researcher from University of São Paulo. The author has contributed to research in topics: Leishmania & Autophagy. The author has an hindex of 17, co-authored 31 publications receiving 952 citations. Previous affiliations of Beatriz S. Stolf include Ludwig Institute for Cancer Research.

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The evolution of two Trypanosoma cruzi subgroups inferred from rRNA genes can be correlated with the interchange of American mammalian faunas in the Cenozoic and has implications to pathogenicity and host specificity.

TL;DR: The agent of Chagas disease, Trypanosoma cruzi, is divided into two highly divergent genetic subgroups, lineages 1 and 2, which include all typed strains isolated from humans, insect vectors, and sylvatic mammals, which are likely to be distinct species, or at least subspecies because of their different ecological and epidemiological traits.
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Protein disulfide isomerase (PDI) associates with NADPH oxidase and is required for phagocytosis of Leishmania chagasi promastigotes by macrophages.

TL;DR: Investigation of the role of PDI in in vitro infection of J774 macrophages by amastigotes and promastigote forms of the protozoan Leishmania chagasi provides evidence that PDI not only associates with phagocyte NADPH oxidase but also thatPDI is crucial for efficient macrophage infection by L. chagasia.
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Epidemiology, biochemistry and evolution of Trypanosoma cruzi lineages based on ribosomal RNA sequences.

TL;DR: The phylogeny of Trypanosoma cruzi reveals major lineages - ribosomal RNA - molecular Epidemiology - molecular epidemiology - phylogeny.
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Comparative analysis of amplified and nonamplified RNA for hybridization in cDNA microarray.

TL;DR: A protocol based on template switch and T7 amplification that led to efficient and linear amplification of 1300x aRNA can be used routinely in cDNA microarray analysis, leading to improved quality of data with high fidelity and reproducibility.