B
Benedek Halmos
Researcher at University Medical Center Groningen
Publications - 5
Citations - 59
Benedek Halmos is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 1, co-authored 1 publications receiving 3 citations.
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Journal ArticleDOI
Cholesterol efflux pathways, inflammation, and atherosclerosis.
TL;DR: The causal relationship between plasma HDL-cholesterol levels and CVD has been called into question by Mendelian randomization studies and the majority of clinical trials not showing any benefit of plasma HDL cholesterol raising drugs on CVD as mentioned in this paper.
Journal ArticleDOI
T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice
Venetia Bazioti,Anouk M. La Rose,Sjors Maassen,Frans Bianchi,Rinse de Boer,Benedek Halmos,Deepti Dabral,Emma Guilbaud,Arthur Flohr-Svendsen,Anouk G. Groenen,Alejandro Marmolejo-Garza,Mirjam H. Koster,Niels J. Kloosterhuis,Rick Havinga,Alle T. Pranger,Miriam Langelaar-Makkinje,Alain de Bruin,B. van de Sluis,Alison B. Kohan,Laurent Yvan-Charvet,Geert van den Bogaart,Marit Westerterp +21 more
TL;DR: In this paper , the effect of cholesterol efflux pathways mediated by ATP-binding cassette A1 and G1 (ABCA1/ABCG1) on T cell-dependent age-related inflammation and atherosclerosis remains poorly understood.
Journal ArticleDOI
Increased atherosclerosis in a mouse model of glycogen storage disease type 1a
Anouk M. La Rose,Anouk G. Groenen,Benedek Halmos,Venetia Bazioti,Martijn G S Rutten,K. A. Krishnamurthy,Mirjam H. Koster,Niels J. Kloosterhuis,Marieke Smit,Rick Havinga,Gilles Mithieux,Fabienne Rajas,Folkert Kuipers,Maaike H. Oosterveer,Marit Westerterp +14 more
TL;DR: This paper found increased atherogenesis in Glycogen storage disease type 1a (GSD Ia) patients compared to age-and-gender matched controls, and employed a mouse model that resembles the severe hyperlipidemia in patients.
Journal ArticleDOI
T-cell Cholesterol Accumulation, Aging, and Atherosclerosis.
TL;DR: In this paper , the effects of T-cell cholesterol accumulation on Tcell fate and atherosclerosis are not uniform, and the extent of T cell cholesterol accumulation and its cellular localization determine T-cells fate and downstream effects on atherosclerotic and Tcell functionality.
Journal ArticleDOI
Statins for ACTA2 mutation-driven atherosclerosis?
TL;DR: In this article , the athero-protective effects of statins in Acta2R149C/Apoe−/− mice may support the cross-talk between smooth muscle cell (SMC) and other cell types in atherosclerotic plaques.