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Showing papers by "Bernard M. Babior published in 1982"

Journal Article•DOI•
Severe recurrent bacterial infections associated with defective adherence and chemotaxis in two patients with neutrophils deficient in a cell-associated glycoprotein.

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Thomas J. Bowen, Hans D. Ochs, Leonard C. Altman, Thomas H. Price, Dennis E. Van Epps, David L. Brautigan, Richard E. Rosin, William D. Perkins, Bernard M. Babior, Seymour J. Klebanoff, Ralph J. Wedgwood 
01 Dec 1982-The Journal of Pediatrics
TL;DR: It is postulated that the glycoprotein deficiency interferes with the migration of polymorphonuclear leukocytes from the bloodstream into the interstitial space and to the site of infection.

186 citations

Book Chapter•DOI•
The Nature and Function of the Microbicidal Oxidase System of Neutrophils

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Anthony W. Segal1, A M Harper1, Rodolpho Garcia1, Owen T.G. Jones2, Andrew R. Cross2, Michael J. Geisow3, Bernard M. Babior •
University College London1, University of Bristol2, National Institute for Medical Research3
01 Jan 1982-Advances in Experimental Medicine and Biology
TL;DR: Stimulated neutrophils demonstrate a burst of nonmitochondrial respiration which appears to be important for the killing of certain bacteria which are killed less efficiently under anaerobic conditions or by cells from patients with Chronic Granulomatous Disease (CGD) which fail to demonstrate this respiratory burst.
Abstract: Stimulated neutrophils demonstrate a burst of nonmitochondrial respiration.1,2 This appears to be important for the killing of certain bacteria which are killed less efficiently under anaerobic conditions,3 or by cells from patients with Chronic Granulomatous Disease (CGD) which fail to demonstrate this respiratory burst.4

7 citations