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Beverly Torok-Storb

Researcher at Fred Hutchinson Cancer Research Center

Publications -  163
Citations -  10882

Beverly Torok-Storb is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Stromal cell & Bone marrow. The author has an hindex of 50, co-authored 160 publications receiving 10506 citations. Previous affiliations of Beverly Torok-Storb include University of Washington & United States Department of Veterans Affairs.

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Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1

TL;DR: It is concluded that antibody STRO-1 binds to BM stromal elements with the capacity to transfer the hematopoietic microenvironment in vitro.
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HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney.

TL;DR: An immortalized adult human PTC line has been established by transduction with HPV 16 E6/E7 genes and it appears to be well-differentiated on the basis of its histochemical, immune cytochemical, and functional characteristics, and it can reproduce experimental results obtained with freshly isolated PTCs.
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The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

TL;DR: Comparison of messenger RNA levels for the 3 major multidrug-resistant efflux pumps, MDR1, MRP1, and ABCG2, in bone marrow SP cells reveals that ABCG 2 is the predominant form in these cells.
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Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells

TL;DR: Human bone marrow-derived CD34+ cells were analyzed for the expression of the beta 1-family of integrin adhesion molecules to identify an adhesion mechanism of potential importance in the localization of primitive progenitors within the hematopoietic microenvironment.
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Functionally Distinct Human Marrow Stromal Cell Lines Immortalized by Transduction With the Human Papilloma Virus E6/E7 Genes

TL;DR: A replication-defective recombinant retrovirus containing the human papilloma virus E6/E7 genes was used to immortalize stromal cells from human marrow, and it is hypothesized that HS-5, HS-21,HS-23, and HS-27 represent functionally distinct components of the marrow microenvironment.