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Bin Tian
Researcher at Shenyang Pharmaceutical University
Publications - 14
Citations - 712
Bin Tian is an academic researcher from Shenyang Pharmaceutical University. The author has contributed to research in topics: Drug delivery & Dissolution testing. The author has an hindex of 10, co-authored 13 publications receiving 577 citations.
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PEG-PLGA copolymers: their structure and structure-influenced drug delivery applications.
TL;DR: PEG-PLGA copolymers are very suitable for the construction of micelles as carriers for insoluble drugs and the structure-influenced drug delivery applications including nanoparticles, micells and hydrogels are examined.
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Increased dissolution and oral absorption of itraconazole/Soluplus extrudate compared with itraconazole nanosuspension.
TL;DR: The results of this study showed increased dissolution and bioavailability of the solid dispersion of the Soluplus-based carrier loading ITZ prepared by HME compared with the ITZ nanosuspension prepared by wet milling.
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Strategies for improving the payload of small molecular drugs in polymeric micelles
Yu Zhang,Tianyang Ren,Jingxin Gou,Ling Zhang,Xiaoguang Tao,Bin Tian,Pengqian Tian,Dandan Yu,Jianbo Song,Xiaolin Liu,Yanhui Chao,Wei Xiao,Xing Tang +12 more
TL;DR: Following an analysis of the published literature, several strategies towards achieving polymeric micelles with high drug loading and stability are presented in this review, in order to ensure adequate drug levels reach target sites.
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A Copper-Mediated Disulfiram-Loaded pH-Triggered PEG-Shedding TAT Peptide-Modified Lipid Nanocapsules for Use in Tumor Therapy.
Ling Zhang,Bin Tian,Yi Li,Tian Lei,Jia Meng,Liu Yang,Yan Zhang,Fen Chen,Fen Chen,Haotian Zhang,Hui Xu,Yu Zhang,Xing Tang +12 more
TL;DR: DSF-S-LNCs increased both the stability and tumor internalization and further increased the cytotoxicity because of the higher copper content, which exhibited higher intracellular uptake and antitumor activity at pH 6.5 than at pH 7.4.
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Polypeptide-based vesicles: formation, properties and application for drug delivery
TL;DR: This article focuses on recent advances involving polypeptide-based vesicles, including their formation and properties, which are significantly different from those of conventional coil–coil copolymers.