B
Bo Jiang
Researcher at Shanghai University
Publications - 27
Citations - 4177
Bo Jiang is an academic researcher from Shanghai University. The author has contributed to research in topics: Medicine & Pharmacokinetics. The author has an hindex of 12, co-authored 14 publications receiving 3640 citations. Previous affiliations of Bo Jiang include Second Military Medical University & Ohio State University.
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Journal ArticleDOI
Human Papillomavirus and Rising Oropharyngeal Cancer Incidence in the United States
Anil K. Chaturvedi,Eric A. Engels,Ruth M. Pfeiffer,Brenda Y. Hernandez,Weihong Xiao,Esther Kim,Bo Jiang,Marc T. Goodman,Maria Sibug-Saber,Wendy Cozen,Lihua Liu,Charles F. Lynch,Nicolas Wentzensen,Richard C.K. Jordan,Sean F. Altekruse,William F. Anderson,Philip S. Rosenberg,Maura L. Gillison +17 more
TL;DR: In this article, the prevalence of human papillomavirus (HPV) infection in oropharyngeal cancer was determined for all 271 oropharygeal cancers (1984-2004) collected by the three population-based cancer registries in the Surveillance, Epidemiology, and End Results (SEER) Residual Tissue Repositories Program.
Journal ArticleDOI
Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability
Keiko Akagi,Jingfeng Li,Tatevik Broutian,Hesed Padilla-Nash,Weihong Xiao,Bo Jiang,James W. Rocco,James W. Rocco,Theodoros N. Teknos,Bhavna Kumar,Danny Wangsa,Dandan He,Thomas Ried,David E. Symer,Maura L. Gillison +14 more
TL;DR: This work presents a model of "looping" by which HPV integrant-mediated DNA replication and recombination may result in viral-host DNA concatemers, frequently disrupting genes involved in oncogenesis and amplifying HPV oncogenes E6 and E7.
Journal ArticleDOI
Validation of methods for oropharyngeal cancer HPV status determination in US cooperative group trials.
Richard C.K. Jordan,Mark W. Lingen,Bayardo Perez-Ordonez,Xin He,Robert K. L. Pickard,Michael Koluder,Bo Jiang,Paul E. Wakely,Weihong Xiao,Maura L. Gillison +9 more
TL;DR: The HPV classification methods used in US cooperative group trials are validated and p16 IHC and HPV16 ISH assays show excellent performance, with high sensitivity and specificity, respectively.
Journal ArticleDOI
Low etiologic fraction for high-risk human papillomavirus in oral cavity squamous cell carcinomas
Mark W. Lingen,Weihong Xiao,Alessandra C. Schmitt,Bo Jiang,Robert K. L. Pickard,Paul Kreinbrink,Bayardo Perez-Ordonez,Richard C.K. Jordan,Maura L. Gillison +8 more
TL;DR: The etiologic fraction for HR-HPV in OCSCC was 5.9% and p16 IHC had poor positive predictive value for detection of HPV in these cancers, which is significantly associated with male gender, small tumor stage, poor tumor differentiation, and basaloid histopathology.
Journal ArticleDOI
Antitussive, expectorant, and bronchodilating effects of quinazoline alkaloids (±)-vasicine, deoxyvasicine, and (±)-vasicinone from aerial parts of Peganum harmala L.
Wei Liu,Yongli Wang,Dandan He,Shuping Li,Yudan Zhu,Bo Jiang,Xuemei Cheng,Zhengtao Wang,Changhong Wang +8 more
TL;DR: Quinazoline alkaloids VAS, VAO, and DVAS have significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.