Zhengtao Wang

TL;DR: In this paper, an activity-directed fractionation and purification process was used to isolate 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) scavenging components from Juglans regia kernels.

TL;DR: Current knowledge of the roles of FXR in physiology of the digestive system and the related diseases is discussed, with a focus on inflammatory bowel disease, colorectal cancer and type 2 diabetes.

TL;DR: This review summarizes the recent advances in the chemical analysis of Danshen and its finished products, including the introduction of the identified bioactive components, analytical methods for quantitative determination of target analytes and fingerprinting authentication, quality criteria ofDanshen crude herb and its preparations, as well as the pharmacokinetic and pharmacodynamic studies on the active components of DANShen andIts finished products.

TL;DR: It is demonstrated that CA prevented APAP-induced hepatotoxicity by decreasing Keap1 expression, inhibiting binding of Keap 1 to NRF2, and thus activating Nrf2 and leading to increased expression of antioxidative signals including HO-1 and NQO1.

TL;DR: The cytotoxic effects of isorhamnetin showed dose- and time-dependency against human hepatocellular carcinoma cells (BEL-7402) with the appearance of a hypodiploid peak (sub-G(0)/G(1) peak), probably due to the presence of cells in apoptosis and apoptotic bodies with DNA content less than 2n.