B
Bow Ho
Researcher at National University of Singapore
Publications - 156
Citations - 5732
Bow Ho is an academic researcher from National University of Singapore. The author has contributed to research in topics: Helicobacter pylori & Lipid A. The author has an hindex of 38, co-authored 156 publications receiving 5256 citations.
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Iron-withholding strategy in innate immunity.
TL;DR: In this review, various vertebrate iron-binding proteins and their invertebrate homologues are introduced so as to impress upon readers an obscured arm of innate immune defense.
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The ancient origin of the complement system
TL;DR: It is shown that the central complement components already existed in the primitive protostome lineage of the horseshoe crab, demonstrating an ancient origin of the critical complement components and the opsonic defense mechanism in the Precambrian ancestor of bilateral animals.
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Zinc-substituted hydroxyapatite: a biomaterial with enhanced bioactivity and antibacterial properties
Eng San Thian,Toshiisa Konishi,Yusuke Kawanobe,Poon Nian Lim,Cleo Choong,Bow Ho,Mamoru Aizawa +6 more
TL;DR: ZnHA possessed enhanced bioactivity since an increase in the growth of human adipose-derived mesenchymal stem cells along with the bone cell differentiation markers, were observed, and antibacterial work demonstrated that ZnHA exhibited antimicrobial capability.
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Respiratory protein-generated reactive oxygen species as an antimicrobial strategy.
TL;DR: It is found that the respiratory proteins of both the horseshoe crab and human were directly activated by microbial proteases and were enhanced by pathogen-associated molecular patterns, resulting in the production of more reactive oxygen species.
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Polycaprolactone-based fused deposition modeled mesh for delivery of antibacterial agents to infected wounds.
Erin Yiling Teo,Shin-Yeu Ong,Mark Seow Khoon Chong,Zhi-Yong Zhang,Jia Lu,Shabbir Moochhala,Bow Ho,Swee Hin Teoh +7 more
TL;DR: 3-dimensional polycaprolactone-tricalcium phosphate mesh incorporated with 15 wt% GS (PT15) efficiently eliminate bacteria within 2 h and demonstrate low cytotoxicity is studied, which shows targeted delivery of antibiotics may provide an efficacious means of infection control through adequate release.