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Bradley R. Monk
Researcher at University of California, San Diego
Publications - 7
Citations - 400
Bradley R. Monk is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Cholinergic & Acetylcholine. The author has an hindex of 5, co-authored 7 publications receiving 323 citations. Previous affiliations of Bradley R. Monk include San Diego State University.
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Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats
TL;DR: Data indicate that choline supplementation during prenatal alcohol exposure may reduce the severity of fetal alcohol effects, particularly on alterations in tasks that require behavioral flexibility, which have important implications for children of women who drink alcohol during pregnancy.
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The effects of perinatal choline supplementation on hippocampal cholinergic development in rats exposed to alcohol during the brain growth spurt
TL;DR: The data suggest that developmental alcohol exposure can cause long‐lasting changes in the hippocampal cholinergic system and that perinatal choline supplementation may attenuate alcohol‐related behavioral changes by influencing cholinerential systems.
Journal ArticleDOI
A neural pathway controlling motivation to exert effort
Christophe D. Proulx,Sage Aronson,Djordje Milivojevic,Cris Molina,Alan Loi,Bradley R. Monk,Steven J. Shabel,Roberto Malinow +7 more
TL;DR: It is shown that one major lateral habenula output pathway controls the motivation to exert effort in both aversive and appetitive contexts, and this pathway may contribute to the reduced motivation in depression.
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Stress transforms lateral habenula reward responses into punishment signals.
TL;DR: It is found that acute stress transforms LHb reward responses into punishment- like neural signals; punishment-like responses to reward omission also increase, which potentially explain why an individual under stress is more prone to depression.
Journal ArticleDOI
Inhibition of PKC disrupts addiction-related memory.
Kristin K. Howell,Bradley R. Monk,Stephanie A. Carmack,Oliver D. Mrowczynski,Robert E. Clark,Stephan G. Anagnostaras +5 more
TL;DR: A novel, critical role for the atypical PKC isoforms in nonassociative memory and cocaine addiction is demonstrated and a single application of ZIP was shown to reduce membrane-bound AMPAR expression.