Brett Hanscom

TL;DR: Patients who underwent surgery showed significantly more improvement in all primary outcomes than did patients who were treated nonsurgically, and the combined as-treated analysis showed a significant advantage for surgery by 3 months for allPrimary outcomes.

TL;DR: Patients in both the surgery and the nonoperative treatment groups improved substantially over a 2-year period, and conclusions about the superiority or equivalence of the treatments are not warranted based on the intent-to-treat analysis.

TL;DR: In nonrandomized as-treated comparisons with careful control for potentially confounding baseline factors, patients with degenerative spondylolisthesis and spinal stenosis treated surgically showed substantially greater improvement in pain and function during a period of 2 years than patients treated nonsurgically.

TL;DR: Patients with persistent sciatica from lumbar disk herniation improved in both operated and usual care groups, and those who chose operative intervention reported greater improvements than patients who elected nonoperative care.

TL;DR: Data demonstrated that age and pretreatment cognitive reserve were related to post-treatment decline in Processing Speed in women exposed to chemotherapy and that chemotherapy had a short-term impact on Verbal Ability.