B
Briallen Lobb
Researcher at University of Waterloo
Publications - 20
Citations - 610
Briallen Lobb is an academic researcher from University of Waterloo. The author has contributed to research in topics: Genome & Phylogenetic tree. The author has an hindex of 8, co-authored 16 publications receiving 372 citations.
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Journal ArticleDOI
AnnoTree: visualization and exploration of a functionally annotated microbial tree of life.
TL;DR: AnnoTree is introduced—an interactive, functionally annotated bacterial tree of life that integrates taxonomic, phylogenetic and functional annotation data from over 27 000 bacterial and 1500 archaeal genomes, and is expected to be a valuable resource for exploring prokaryotic gene histories.
Journal ArticleDOI
Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue.
Jennifer A. Aguiar,Benjamin J.-M. Tremblay,Michael J. Mansfield,Owen Z. Woody,Briallen Lobb,Arinjay Banerjee,Abiram Chandiramohan,Nicholas Tiessen,Quynh T. Cao,Anna Dvorkin-Gheva,Spencer Revill,Matthew S. Miller,Christopher Carlsten,Louise Organ,Chitra Joseph,Alison E. John,Paul J. Hanson,Richard C. Austin,Bruce M. McManus,Gisli Jenkins,Karen L. Mossman,Kjetil Ask,Andrew C. Doxey,Andrew C. Doxey,Jeremy A. Hirota +24 more
TL;DR: The data suggest the presence of a mechanism dynamically regulating ACE2 expression in human lung, perhaps in periods of SARS-CoV-2 infection, and also suggest that alternative receptors for SAR's coronavirus exist to facilitate initial host cell infection.
Posted ContentDOI
Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue
Jennifer A. Aguiar,Benjamin J.-M. Tremblay,Michael J. Mansfield,Owen Z. Woody,Briallen Lobb,Arinjay Banerjee,Abiram Chandiramohan,Nicholas Tiessen,Anna Dvorkin-Gheva,Spencer Revill,Matthew S. Miller,Christopher Carlsten,Louise Organ,Chitra Joseph,Alison E. John,Paul J. Hanson,Bruce M. McManus,Gisli Jenkins,Karen L. Mossman,Kjetil Ask,Andrew C. Doxey,Andrew C. Doxey,Jeremy A. Hirota +22 more
TL;DR: The data suggest the presence of a mechanism dynamically regulating ACE2 expression in human lung, perhaps in periods of SARS-CoV-2 infection, and also suggest that alternate receptors for Sars-Cov-2 exist to facilitate initial host cell infection.
Journal ArticleDOI
An assessment of genome annotation coverage across the bacterial tree of life
TL;DR: The analysis of bacterial genomes from the Genome Taxonomy Database revealed that 52 and 79 % of the average bacterial proteome could be functionally annotated based on protein and domain-based homology searches, respectively, highlighting the disparity in annotation coverage.
Journal ArticleDOI
MetAnnotate: function-specific taxonomic profiling and comparison of metagenomes.
TL;DR: MetAnnotate is a useful framework for general and/or function-specific taxonomic profiling and comparison of metagenomes that achieves high taxonomic classification accuracy for a broad range of genes, including both markers of community abundance and specific biological pathways.