Brian Burkel

TL;DR: Fluorescent F-actin probes are described based on the calponin homology domain of utrophin (Utr-CH), which binds F-actsin without stabilizing it in vitro, and it is shown that these probes faithfully report the distribution of F-Actin in living and fixed cells, distinguish between stable and dynamic F- actin, and have no obvious effects on processes that depend critically on the balance of actin assembly and disassembly.

TL;DR: It is found that cytoplasmic anthocyanin aggregates in close contact with the vacuolar surface are directly engulfed by the vacUolar membrane in a process reminiscent of microautophagy.

TL;DR: It is shown that changes in density of the collagen microenvironment can modulate metabolic shifts of cancer cells, and under high density conditions the contribution of glutamine as a fuel source to drive the TCA cycle was significantly enhanced.

TL;DR: Directional gradients in Rho GTPase turnover impart directional information to contractile arrays, and proper functioning of these gradients is dependent on both contraction and F-actin turnover.

TL;DR: This work has given insight into both the membrane fusion and cytoskeletal responses to plasma membrane damage and it is proposed that Rho GTPase activation results at least in part from the events that drive membrane repair.