B
Brian K.H. Yu
Researcher at The Chinese University of Hong Kong
Publications - 15
Citations - 1343
Brian K.H. Yu is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Cancer & Survival rate. The author has an hindex of 10, co-authored 14 publications receiving 1223 citations.
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Journal ArticleDOI
Prospective Randomized Study of Intensity-Modulated Radiotherapy on Salivary Gland Function in Early-Stage Nasopharyngeal Carcinoma Patients
Michael K.M. Kam,Sing Fai Leung,Benny Zee,Ricky M. C. Chau,Joyce J. S. Suen,Frankie Mo,Maria Lai,Rosalie Ho,Kin Yin Cheung,Brian K.H. Yu,Samuel K.W. Chiu,Peter H.K. Choi,Peter M.L. Teo,Wing Hong Kwan,Anthony T.C. Chan +14 more
TL;DR: IMRT is superior to 2DRT in preserving parotid function and results in less severe delayed xerostomia in the treatment of early-stage NPC, which reflects the need to enhance protection of other salivary glands.
Journal ArticleDOI
Randomized Phase II Trial of Concurrent Cisplatin-Radiotherapy With or Without Neoadjuvant Docetaxel and Cisplatin in Advanced Nasopharyngeal Carcinoma
Edwin P. Hui,Brigette B.Y. Ma,Sing F. Leung,Ann D. King,Frankie Mo,Michael K. Kam,Brian K.H. Yu,Samuel K. Chiu,Wing H. Kwan,Rosalie Ho,Iris H.S. Chan,Anil T. Ahuja,Benny Zee,Anthony T.C. Chan +13 more
TL;DR: Neoadjuvant docetaxel-cisplatin followed by CRT was well tolerated with a manageable toxicity profile that allowed subsequent delivery of full-dose CRT and preliminary results suggested a positive impact on survival.
Journal ArticleDOI
Prognostic significance of the total dose of cisplatin administered during concurrent chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma.
Herbert H. Loong,Brigette B.Y. Ma,Sing Fai Leung,Frankie Mo,Edwin P. Hui,Michael K. Kam,Stephen L. Chan,Brian K.H. Yu,Anthony T.C. Chan +8 more
TL;DR: Number of cycles of cisplatin delivered is an independent prognostic factor in patients with stage II-III NPC undergoing CRT with weekly cisPlatin, and is significantly associated with survival in the univariate but not the multivariate analysis.
Journal ArticleDOI
Plasma osteopontin, hypoxia, and response to radiotherapy in nasopharyngeal cancer.
Edwin P. Hui,Fion L. Sung,Brian K.H. Yu,Cesar S. C. Wong,Brigette B.Y. Ma,Xiaorong Lin,Andrew T. Chan,Wai Lap Wong,Anthony T.C. Chan +8 more
TL;DR: The results suggested that the pretreatment plasma osteopontin level may be a useful biomarker of response to radiotherapy in nasopharyngeal carcinoma.
Journal ArticleDOI
Surgical salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma: a multivariate analysis of prognostic factors.
Alexander C. Vlantis,Hing Sang Chan,Michael C. F. Tong,Brian K.H. Yu,Michael K.M. Kam,C. Andrew van Hasselt +5 more
TL;DR: The purpose of this study was to identify independent prognostic factors that influenced local relapse‐free survival (LRFS) and overall survival (OS) of patients who underwent salvage surgery for residual or recurrent nasopharyngeal carcinoma (NPC).