S
Sing Fai Leung
Researcher at The Chinese University of Hong Kong
Publications - 126
Citations - 10169
Sing Fai Leung is an academic researcher from The Chinese University of Hong Kong. The author has contributed to research in topics: Nasopharyngeal carcinoma & Carcinoma. The author has an hindex of 47, co-authored 126 publications receiving 9376 citations.
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Journal Article
Quantitative Analysis of Cell-free Epstein-Barr Virus DNA in Plasma of Patients with Nasopharyngeal Carcinoma
Y.M. Dennis Lo,Lisa Y.S. Chan,Kwok Wai Lo,Sing Fai Leung,Jun Zhang,Anthony T.C. Chan,Joseph C.K. Lee,N. Magnus Hjelm,Philip J. Johnson,Dolly P. Huang +9 more
TL;DR: Results suggest that quantitative analysis of plasma EBV DNA may be a useful clinical and research tool in the screening and monitoring of NPC patients.
Journal ArticleDOI
Prospective Randomized Study of Intensity-Modulated Radiotherapy on Salivary Gland Function in Early-Stage Nasopharyngeal Carcinoma Patients
Michael K.M. Kam,Sing Fai Leung,Benny Zee,Ricky M. C. Chau,Joyce J. S. Suen,Frankie Mo,Maria Lai,Rosalie Ho,Kin Yin Cheung,Brian K.H. Yu,Samuel K.W. Chiu,Peter H.K. Choi,Peter M.L. Teo,Wing Hong Kwan,Anthony T.C. Chan +14 more
TL;DR: IMRT is superior to 2DRT in preserving parotid function and results in less severe delayed xerostomia in the treatment of early-stage NPC, which reflects the need to enhance protection of other salivary glands.
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Chemotherapy in locally advanced nasopharyngeal carcinoma: An individual patient data meta-analysis of eight randomized trials and 1753 patients
Bertrand Baujat,Hélène Audry,Jean Bourhis,Anthony T.C. Chan,Haluk Onat,Daniel T.T. Chua,Dora L.W. Kwong,Muhyi Al-Sarraf,Kwan Hwa Chi,Masato Hareyama,Sing Fai Leung,Kullathorn Thephamongkhol,Jean Pierre Pignon +12 more
TL;DR: Chemotherapy led to a small, but significant, benefit for overall survival and event-free survival when chemotherapy was administered concomitantly with RT.
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Treatment of nasopharyngeal carcinoma with intensity-modulated radiotherapy: the Hong Kong experience.
Michael K.M. Kam,Peter M.L. Teo,Ricky M. C. Chau,Kin Yin Cheung,Peter H.K. Choi,Wing Hong Kwan,Sing Fai Leung,Benny Zee,Anthony T.C. Chan +8 more
TL;DR: The authors' experience of using IMRT in the primary treatment of NPC showed a very high rate of locoregional control and favorable toxicity profile, and it was found that dose escalation above 66 Gy of IMRT-based therapy was a significant determinant of progression- free survival and distant metastasis-free survival for advanced T-stage tumors.
Journal ArticleDOI
Analysis of Plasma Epstein-Barr Virus DNA to Screen for Nasopharyngeal Cancer.
K.C. Allen Chan,John K. S. Woo,Ann D. King,Benny Zee,W K Jacky Lam,Stephen L. Chan,Sam W I Chu,Constance Mak,Irene O L Tse,Samantha Y M Leung,Gloria Chan,Edwin P. Hui,Brigette B.Y. Ma,Rossa W.K. Chiu,Sing Fai Leung,Andrew van Hasselt,Anthony T.C. Chan,Y.M. Dennis Lo +17 more
TL;DR: Analysis of EBV DNA in plasma samples was useful in screening for early asymptomatic nasopharyngeal carcinoma and outcomes were better in participants who were identified by screening than in those in a historical cohort.