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Brian T. Joyce
Researcher at Northwestern University
Publications - 75
Citations - 2275
Brian T. Joyce is an academic researcher from Northwestern University. The author has contributed to research in topics: Medicine & DNA methylation. The author has an hindex of 17, co-authored 56 publications receiving 1785 citations. Previous affiliations of Brian T. Joyce include Rush University Medical Center & University of Illinois at Chicago.
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Journal ArticleDOI
A Meta-analysis of the Incidence of Anterior Cruciate Ligament Tears as a Function of Gender, Sport, and a Knee Injury–Reduction Regimen
TL;DR: Meta-analysis was applied to the entire applicable literature to generate accurate estimates of the true incidences of ACL tear as a function of gender, sport, and injury-reduction training and found female subjects had a roughly 3 times greater incidence of ACL tears in soccer and basketball versus male subjects.
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A meta-analysis of stability of autografts compared to allografts after anterior cruciate ligament reconstruction.
TL;DR: It would appear that autografts are the graft of choice for routine ACLR with allografteds better reserved for multiple ligament-injured knees where extra tissue may be required.
Journal ArticleDOI
Blood Epigenetic Age may Predict Cancer Incidence and Mortality
Yinan Zheng,Brian T. Joyce,Brian T. Joyce,Elena Colicino,Lei Liu,Wei Zhang,Qi Dai,Martha J. Shrubsole,Warren A. Kibbe,Tao Gao,Zhou Zhang,Nadereh Jafari,Pantel S. Vokonas,Joel Schwartz,Andrea A. Baccarelli,Lifang Hou +15 more
TL;DR: It is concluded that blood epigenetic age may mirror epigenetic abnormalities related to cancer development, potentially serving as a minimally invasive biomarker for cancer early detection.
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A meta-analysis of stability after anterior cruciate ligament reconstruction as a function of hamstring versus patellar tendon graft and fixation type.
TL;DR: The recent literature would suggest that 4HS ACLR produces higher stability rates than BPTB, that 4 HS stability rates are fixation dependent, that aperture fixation offers no stability advantage, and that EndoButton with second-generation tibial fixation produces consistently high stability rates.
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Estimating and testing high-dimensional mediation effects in epigenetic studies.
Haixiang Zhang,Yinan Zheng,Zhou Zhang,Tao Gao,Brian T. Joyce,Grace Yoon,Wei Zhang,Joel Schwartz,Allan C. Just,Elena Colicino,Pantel S. Vokonas,Lihui Zhao,Jinchi Lv,Andrea A. Baccarelli,Lifang Hou,Lei Liu +15 more
TL;DR: This work uses a joint significance test for mediation effect and applies this method to investigate the extent to which DNA methylation markers mediate the causal pathway from smoking to reduced lung function in the Normative Aging Study.