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Brooke Tata
Researcher at university of lille
Publications - 3
Citations - 307
Brooke Tata is an academic researcher from university of lille. The author has contributed to research in topics: GnRH Neuron & Congenital Hypogonadotropic Hypogonadism. The author has an hindex of 2, co-authored 3 publications receiving 190 citations. Previous affiliations of Brooke Tata include French Institute of Health and Medical Research.
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Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood
Brooke Tata,Brooke Tata,Nour El Houda Mimouni,Nour El Houda Mimouni,Anne-Laure Barbotin,Samuel A. Malone,Samuel A. Malone,Anne Loyens,Anne Loyens,Pascal Pigny,Didier Dewailly,Didier Dewailly,Sophie Catteau-Jonard,Sophie Catteau-Jonard,Inger Sundström-Poromaa,Terhi Piltonen,Federica Dal Bello,Claudio Medana,Vincent Prevot,Vincent Prevot,Jerome Clasadonte,Jerome Clasadonte,Paolo Giacobini,Paolo Giacobini +23 more
TL;DR: A critical role is highlighted for excess prenatal AMH exposure and subsequent aberrant GnRH receptor signaling in the neuroendocrine dysfunctions of PCOS, while offering a new potential therapeutic avenue to treat the condition during adulthood.
Journal ArticleDOI
DCC/NTN1 complex mutations in patients with congenital hypogonadotropic hypogonadism impair GnRH neuron development
Justine Bouilly,Andrea Messina,Georgios Papadakis,Daniele Cassatella,Cheng Xu,James S. Acierno,Brooke Tata,Brooke Tata,Gerasimos P. Sykiotis,Sara Santini,Yisrael Sidis,Eglantine Elowe-Gruau,Franziska Phan-Hug,Michael Hauschild,Pierre-Marc Bouloux,Richard Quinton,Mariarosaria Lang-Muritano,Lucie Favre,Laura Marino,Paolo Giacobini,Paolo Giacobini,Andrew A. Dwyer,Andrew A. Dwyer,Nicolas J Niederländer,Nelly Pitteloud +24 more
TL;DR: This study implicates DCC and NTN1 mutations in the pathophysiology of CHH consistent with the role of these two genes in the ontogeny of GnRH neurons in mice.
Journal ArticleDOI
DCC/NTN1 complex mutations in patients with congenital hypogonadotropic hypogonadism impair GnRH neuron development
Justine Bouilly,Andrea Messina,Georgios Papadakis,Daniele Cassatella,Xu C,James S Acierno,Brooke Tata,Gerasimos P. Sykiotis,antini S,Yisrael Sidis,lowe-Gruau E,Franziska Phan-Hug,Michael Hauschild,P.-M. G. Bouloux,Richard Quinton,Lang-uritano M,Lucie Favre,Laura Marino,Paolo Giacobini,Andrew A. Dwyer,Nicolas J Niederländer,Nelly Pitteloud +21 more
TL;DR: Justine Bouilly, Andrea Messina, Georgios Papadakis, Daniele Cassatella, Cheng Xu, James S. Acierno, Gerasimos Sykiotis, Sara Santini, Yisrael Sidis, Franziska Phan-Hug, Michael Hauschild, Pierre-Marc Bouloux, Richard Quinton, Mariarosaria LangMuritano, Lucie Favre, Laura Marino, Paolo Giacobini.