B
Brown J. Okoko
Researcher at Medical Research Council
Publications - 14
Citations - 784
Brown J. Okoko is an academic researcher from Medical Research Council. The author has contributed to research in topics: Population & Pneumococcal conjugate vaccine. The author has an hindex of 11, co-authored 14 publications receiving 751 citations.
Papers
More filters
Journal ArticleDOI
Immunogenicity and safety of a meningococcal A conjugate vaccine in Africans.
Samba O. Sow,Brown J. Okoko,Aldiouma Diallo,Simonetta Viviani,Ray Borrow,George M. Carlone,Milagritos D. Tapia,Adebayo Akinsola,Pascal Arduin,Helen Findlow,Cheryl M. Elie,Fadima Cheick Haidara,Richard A. Adegbola,Doudou Diop,Varsha Parulekar,Julie Chaumont,Lionel Martellet,Fatoumata Diallo,Olubukola T. Idoko,Yuxiao Tang,Brian D. Plikaytis,Prasad S. Kulkarni,Elisa Marchetti,F. Marc LaForce,Marie-Pierre Préziosi +24 more
TL;DR: The PsA-TT vaccine elicited a stronger response to group A antibody than the PsACWY vaccine, and had obvious immunologic memory after receiving a polysaccharide booster vaccine.
Journal ArticleDOI
Epidemiologic and Clinical Characteristics of Community-Acquired Invasive Bacterial Infections in Children Aged 2–29 Months in The Gambia
Godwin Enwere,Ekow Biney,Yin Bun Cheung,Syed M. A. Zaman,Brown J. Okoko,Claire Oluwalana,Adeola Vaughan,Brian Greenwood,Richard A. Adegbola,Felicity T. Cutts +9 more
TL;DR: Although vaccines could greatly reduce the pneumococcal burden, a high index of suspicion and appropriate use of antimicrobials are needed to manage other causes of invasive bacterial infections.
Journal ArticleDOI
The Influence of Placental Malaria Infection and Maternal Hypergammaglobulinemia on Transplacental Transfer of Antibodies and IgG Subclasses in a Rural West African Population
Brown J. Okoko,Lalanga H. Wesumperuma,Martin O. C. Ota,Margaret Pinder,Winston A. S. Banya,Silver F. Gomez,Keith P. W. J. McAdam,Anthony C. Hart +7 more
TL;DR: Placental malaria infection and maternal hypergammaglobulinemia were associated with reduction in the transplacental transfer of these specific antibodies, IgG1, and IgG2 in this Gambian population.
Journal ArticleDOI
Influence of Placental Malaria Infection on Foetal Outcome in the Gambia: Twenty years after Ian McGregor
Brown J. Okoko,Martin O. C. Ota,Lawrence Yamuah,David Idiong,Stella N. Mkpanam,Akum Avieka,Winston A. S. Banya,Kike Osinusi +7 more
TL;DR: The findings of the present study suggest undertaking of effective malaria-control strategies during pregnancy, such as use of insecticide-impregnated bednets, intermittent and early treatment for malaria, and antimalarial chemoprophylaxis, in the Gambia.
Journal ArticleDOI
Influence of placental malaria infection and maternal hypergammaglobulinaemia on materno-foetal transfer of measles and tetanus antibodies in a rural west African population.
Brown J. Okoko,Lalanga H. Wesuperuma,Martin O. C. Ota,Winston A. S. Banya,Margaret Pinder,Felix S. Gomez,Keke Osinusi,Anthony C. Hart +7 more
TL;DR: It is concluded that the combined influence of placental malaria infection and maternal hypergammaglobulinaemia is significantly associated with the transfer of impaired measles antibody in this population.