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Bruce A. Barut
Researcher at Howard Hughes Medical Institute
Publications - 33
Citations - 4804
Bruce A. Barut is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Zebrafish & Positional cloning. The author has an hindex of 24, co-authored 33 publications receiving 4587 citations. Previous affiliations of Bruce A. Barut include Boston Children's Hospital & Harvard University.
Papers
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Journal ArticleDOI
The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish.
Julio D. Amigo,Julio D. Amigo,Gabriele E. Ackermann,John J. Cope,Ming Yu,Jeffrey D. Cooney,Dongdong Ma,Nathaniel B. Langer,Ebrahim Shafizadeh,George C. Shaw,Wyatt Horsely,Nikolaus S. Trede,Nikolaus S. Trede,Alan J. Davidson,Alan J. Davidson,Bruce A. Barut,Yi Zhou,Yi Zhou,Sarah A. Wojiski,Sarah A. Wojiski,David Traver,Tyler B. Moran,George Kourkoulis,Karl Hsu,John P. Kanki,Dhvanit I. Shah,Hui Feng Lin,Robert I. Handin,Robert I. Handin,Alan B. Cantor,Alan B. Cantor,Barry H. Paw +31 more
TL;DR: Zebrafish FOG-1 is expressed in early hematopoietic cells, as well as heart, viscera, and paraspinal neurons, suggesting that it has multifaceted functions in organogenesis, and 2 cis-regulatory elements that control the tissue-specific gene expression of Fog-1 are identified.
Journal ArticleDOI
Zebrafish slc4a2/ae2 anion exchanger: cDNA cloning, mapping, functional characterization, and localization.
Boris E. Shmukler,Christine E. Kurschat,Gabriele E. Ackermann,Lianwei Jiang,Yi Zhou,Bruce A. Barut,Alan K. Stuart-Tilley,Jinhua Zhao,Leonard I. Zon,Iain A. Drummond,David H. Vandorpe,Barry H. Paw,Seth L. Alper +12 more
TL;DR: Zebrafish Ae2 resembles its mammalian orthologs in function, mechanism, and acute regulation but differs in its preferentially apical expression in kidney, which will inform tests of the role of Ae2 in zebrafish kidney development and function.
Patent
Methods for using the obese gene and its gene product to stimulate hematopoietic development
H. Ralph Snodgrass,Joseph Cioffi,Thomas Joel Zupancic,Alan W. Shafer,Adel A. Mikhail,Bruce A. Barut +5 more
TL;DR: In this article, the expression of various forms of a novel receptor in hematopoietic and endothelial cells has been investigated and a variant form of this receptor has been detected in brain cells and shown to bind to the obese gene product, leptin.
Journal ArticleDOI
Lack of a role of interleukin 11 in the growth of multiple myeloma.
TL;DR: It is strongly suggested that IL-11 does support the growth of a murine plasmacytoma cell line but does not play a role in thegrowth of either freshly isolated human myeloma cells or derived cell lines.
Journal ArticleDOI
Response patterns of hairy cell leukemia to B-cell mitogens and growth factors
TL;DR: IL-4, IL-5, and IL-6 mediated DNA synthesis by HCLs in vitro is demonstrated and a possible in vivo role for these growth factors in the pathophysiology of HCL is suggested.