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Bruce E. Johnson
Researcher at Harvard University
Publications - 523
Citations - 76494
Bruce E. Johnson is an academic researcher from Harvard University. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 104, co-authored 474 publications receiving 68801 citations. Previous affiliations of Bruce E. Johnson include University of Adelaide & Virginia Tech.
Papers
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Journal Article
myc family DNA amplification in 107 tumors and tumor cell lines from patients with small cell lung cancer treated with different combination chemotherapy regimens.
John Brennan,Theresa Z. O'Connor,Robert W. Makuch,Alfreda Simmons,Edward K. Russell,R. Ilona Linnoila,Ruby Phelps,Adi F. Gazdar,Daniel C. Ihde,Bruce E. Johnson +9 more
TL;DR: It is concluded that there are no prominent differences in the frequency of amplification following treatment with different chemotherapy regimens; and the myc family DNA amplification is similar in tumors and tumor cell lines from the same patients.
Journal ArticleDOI
Antitumor Activity of a Monoclonal Antibody Directed Against Gastrin-Releasing Peptide in Patients With Small Cell Lung Cancer
Michael J. Kelley,R. Ilona Linnoila,Ingalill Avis,Mark S. Georgiadis,Frank Cuttitta,James L. Mulshine,Bruce E. Johnson +6 more
TL;DR: Interruption of the GRP autocrine growth factor loop with 2A11 results in clinical antitumor activity in a minority of patients with previously treated SCLC.
Patent
Methods and apparatus for switching Fibre Channel Arbitrated Loop devices
Bruce Gregory Warren,William Goodwin,Carl Joseph Mies,Michael L. White,Warren Eng,Bruce E. Johnson +5 more
TL;DR: In this article, the authors describe a fiber-channel Arbitrated Loop System (FLS) with a number of arbitrated loop primitives, such as ARB, OPN and CLS.
Journal Article
A Phase II Study of Weekly Paclitaxel in Elderly Patients with Advanced Non-Small Cell Lung Cancer
Panos Fidias,Jeffrey G. Supko,Renato G. Martins,Anthony L. Boral,Robert W. Carey,Michael L. Grossbard,Geoffrey I. Shapiro,Patricia Ostler,Joan Lucca,Bruce E. Johnson,Arthur T. Skarin,Thomas J. Lynch +11 more
TL;DR: Paclitaxel administered as a weekly 1-h infusion at a dose of 90 mg/m(2) is a safe and effective therapy for elderly patients with advanced non-small cell lung cancer.
Journal ArticleDOI
Estimating Long-term Effectiveness of Lung Cancer Screening in the Mayo CT Screening Study
Pamela M. McMahon,Chung Yin Kong,Bruce E. Johnson,Milton C. Weinstein,Jane C. Weeks,Karen M. Kuntz,Karen M. Kuntz,Jo-Anne O. Shepard,Stephen J. Swensen,G. Scott Gazelle +9 more
TL;DR: Screening may reduce lung cancer-specific mortality but may offer a smaller reduction in overall mortality because of increased competing mortality risks associated with smoking.