B
Bruce E. Johnson
Researcher at Harvard University
Publications - 523
Citations - 76494
Bruce E. Johnson is an academic researcher from Harvard University. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 104, co-authored 474 publications receiving 68801 citations. Previous affiliations of Bruce E. Johnson include University of Adelaide & Virginia Tech.
Papers
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Journal ArticleDOI
NCI-Navy Medical Oncology Branch cell line data base
Ruby Phelps,Bruce E. Johnson,Daniel C. Ihde,Adi F. Gazdar,David P. Carbone,Patrick R. McClintock,R. Ilona Linnoila,Mary J. Matthews,Paul A. Bunn,Desmond N. Carney,John D. Minna,James L. Mulshine +11 more
TL;DR: The cell line data base described in this paper includes both clinical information about the patients from whom the cell line were derived and informationabout the in vitro analyses performed of the cell lines.
Journal ArticleDOI
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
Michal Slyper,Caroline B. M. Porter,Orr Ashenberg,Julia Waldman,Eugene Drokhlyansky,Isaac Wakiro,Isaac Wakiro,Christopher Smillie,Gabriela Smith-Rosario,Jingyi Wu,Jingyi Wu,Danielle Dionne,Sébastien Vigneau,Sébastien Vigneau,Judit Jané-Valbuena,Timothy L. Tickle,Sara Napolitano,Sara Napolitano,Mei-Ju Su,Mei-Ju Su,Anand G. Patel,Asa Karlstrom,Simon Gritsch,Masashi Nomura,Avinash Waghray,Satyen H. Gohil,Satyen H. Gohil,Alexander M. Tsankov,Alexander M. Tsankov,Livnat Jerby-Arnon,Ofir Cohen,Ofir Cohen,Johanna Klughammer,Yanay Rosen,Joshua Gould,Lan Nguyen,Matan Hofree,Peter J. Tramontozzi,Bo Li,Bo Li,Catherine J. Wu,Benjamin Izar,Rizwan Haq,Rizwan Haq,F. Stephen Hodi,Charles H. Yoon,Charles H. Yoon,Aaron N. Hata,Suzanne J. Baker,Mario L. Suvà,Mario L. Suvà,Raphael Bueno,Elizabeth H. Stover,Elizabeth H. Stover,Michael R. Clay,Michael A. Dyer,Michael A. Dyer,Natalie B. Collins,Natalie B. Collins,Natalie B. Collins,Ursula A. Matulonis,Nikhil Wagle,Bruce E. Johnson,Asaf Rotem,Asaf Rotem,Orit Rozenblatt-Rosen,Aviv Regev,Aviv Regev,Aviv Regev +68 more
TL;DR: A set of ready-to-use tools for profiling fresh and frozen clinical tumor samples using scRNA-Seq and snRNA- Seq facilitates the implementation of single-cell technologies in clinical settings and the construction ofsingle-cell tumor atlases.
Journal Article
Regulation of Cellular Proliferation, Cytoskeletal Function, and Signal Transduction through CXCR4 and c-Kit in Small Cell Lung Cancer Cells
Takashi Kijima,Gautam Maulik,Patrick C. Ma,Elena V. Tibaldi,Ross E. Turner,Barrett J. Rollins,Martin Sattler,Bruce E. Johnson,Ravi Salgia +8 more
TL;DR: It is found that SDF-1alpha dramatically increased cell motility and adhesion in CXCR4-expressing NCI-H446 SCLC cells and may, therefore, be involved in the pathogenesis of SclC in vivo.
Journal ArticleDOI
The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution
Orit Rozenblatt-Rosen,Aviv Regev,Aviv Regev,Aviv Regev,Philipp Oberdoerffer,Tal Nawy,Anna Hupalowska,Jennifer Rood,Orr Ashenberg,Ethan Cerami,Robert J. Coffey,Emek Demir,Li Ding,Edward D. Esplin,James M. Ford,Jeremy Goecks,Sharmistha Ghosh,Joe W. Gray,Justin Guinney,Justin Guinney,Sean E. Hanlon,Shannon K. Hughes,E. Shelley Hwang,Christine A. Iacobuzio-Donahue,Judit Jané-Valbuena,Bruce E. Johnson,Ken S. Lau,Tracy Lively,Sarah A. Mazzilli,Dana Pe'er,Sandro Santagata,Sandro Santagata,Alex K. Shalek,Denis Schapiro,Denis Schapiro,Michael Snyder,Peter K. Sorger,Avrum E. Spira,Avrum E. Spira,Sudhir Srivastava,Kai Tan,Kai Tan,Robert West,Elizabeth H. Williams,Elizabeth H. Williams,Denise Aberle,Samuel Achilefu,Foluso O. Ademuyiwa,Andrew Adey,Rebecca Aft,Rachana Agarwal,Ruben A. Aguilar,Fatemeh Alikarami,Viola Allaj,Christopher I. Amos,Robert A. Anders,Michael R. Angelo,Kristen Anton,Jon C. Aster,Özgün Babur,Amir Bahmani,Akshay Balsubramani,David M. Barrett,Jennifer Beane,Diane Bender,Kathrin M. Bernt,Lynne D. Berry,Courtney Betts,Julie Bletz,Katie Blise,Adrienne Boire,Genevieve M. Boland,Alexander D. Borowsky,Kristopher R. Bosse,Matthew J. Bott,Edward S. Boyden,James D. Brooks,Raphael Bueno,Erik A. Burlingame,Qiuyin Cai,Joshua D. Campbell,Wagma Caravan,Hassan Chaib,Joseph M. Chan,Young Hwan Chang,Deyali Chatterjee,Ojasvi Chaudhary,Alyce A. Chen,Bob Chen,Changya Chen,Chia hui Chen,Feng Chen,Yuan Chen,Milan G. Chheda,Koei Chin,Roxanne Chiu,Shih Kai Chu,Rodrigo Chuaqui,Jaeyoung Chun,Luis Cisneros,Graham A. Colditz,Kristina A. Cole,Natalie B. Collins,Kévin Contrepois,Lisa M. Coussens,Allison L. Creason,Daniel J. Crichton,Christina Curtis,Tanja M. Davidsen,Sherri R. Davies,Ino de Bruijn,Laura DelloStritto,Angelo M. De Marzo,David G. DeNardo,Dinh Diep,Sharon J. Diskin,Xengie Doan,Julia L. Drewes,Stephen Dubinett,Michael A. Dyer,Jacklynn V. Egger,Jennifer Eng,Barbara E. Engelhardt,Graham Erwin,Laura J. Esserman,Alex Felmeister,Heidi S. Feiler,Ryan C. Fields,Stephen A. Fisher,Keith T. Flaherty,Jennifer Flournoy,Angelo Fortunato,Allison Frangieh,Jennifer L. Frye,Robert S. Fulton,Danielle Galipeau,Siting Gan,Jianjiong Gao,Long Gao,Peng Gao,Vianne R. Gao,Tim Geiger,Ajit George,Gad Getz,Marios Giannakis,David L Gibbs,William E. Gillanders,Simon P. Goedegebuure,Alanna Gould,Kate H.C. Gowers,William J. Greenleaf,Jeremy Gresham,Jennifer L. Guerriero,Tuhin Kumar Guha,Alexander R. Guimaraes,David A. Gutman,Nir Hacohen,Sean E. Hanlon,Casey R. Hansen,Olivier Harismendy,Kathleen A. Harris,Aaron N. Hata,Akimasa Hayashi,Cody N. Heiser,Karla Helvie,John M. Herndon,Gilliam Hirst,Frank Hodi,Travis J. Hollmann,Aaron M. Horning,James J. Hsieh,Shannon Hughes,Won Jae Huh,Stephen P. Hunger,Shelley Hwang,Heba Ijaz,Benjamin Izar,Connor A. Jacobson,Sam M. Janes,Reyka G Jayasinghe,Lihua Jiang,Brett Johnson,Bruce E. Johnson,Tao Ju,Humam Kadara,Klaus H. Kaestner,Jacob Kagan,Lukas Kalinke,Robert L. Keith,Aziz Khan,Warren A. Kibbe,Albert H. Kim,Erika Kim,Junhyong Kim,Annette Kolodzie,Mateusz Kopytra,Eran Kotler,Robert Krueger,Kostyantyn Krysan,Anshul Kundaje,Uri Ladabaum,Blue B. Lake,Huy Lam,Rozelle Laquindanum,Ashley M. Laughney,Hayan Lee,Marc E. Lenburg,Carina A. Leonard,Ignaty Leshchiner,Rochelle Levy,Jerry Li,Christine G. Lian,Kian-Huat Lim,Jia-Ren Lin,Yiyun Lin,Qi Liu,Ruiyang Liu,William J.R. Longabaugh,Teri A. Longacre,Cynthia X. Ma,Mary Catherine Macedonia,Tyler Madison,Christopher G. Maher,Anirban Maitra,Netta Makinen,Danika Makowski,Carlo C. Maley,Zoltan Maliga,Diego Mallo,John M. Maris,Nick Markham,Jeffrey R. Marks,Daniel Martinez,Robert J. Mashl,Ignas Masilionais,Jennifer Mason,Joan Massagué,Pierre P. Massion,Marissa Mattar,Richard Mazurchuk,Linas Mazutis,Eliot T. McKinley,Joshua F. McMichael,Daniel T. Merrick,Matthew Meyerson,Julia R. Miessner,Gordon B. Mills,Meredith A. Mills,Suman B. Mondal,Motomi Mori,Yuriko Mori,Elizabeth Moses,Yael P. Mosse,Jeremy L. Muhlich,George F. Murphy,Nicholas Navin,Michel Nederlof,Reid M. Ness,Stephanie A. Nevins,Milen Nikolov,Ajit J. Nirmal,Garry P. Nolan,Edward Novikov,Brendan O'Connell,Michael Offin,Stephen T. Oh,Anastasiya Olson,Alex Ooms,Miguel Ossandon,Kouros Owzar,Swapnil Parmar,Tasleema Patel,Gary J. Patti,Itsik Pe'er,Tao Peng,Daniel Persson,Marvin Petty,Hanspeter Pfister,Kornelia Polyak,Kamyar Esmaeili Pourfarhangi,Sidharth V. Puram,Qi Qiu,Álvaro Quintanal-Villalonga,Arjun Raj,Marisol A. Ramirez-Solano,Rumana Rashid,Ashley N. Reeb,Mary E. Reid,Adam C. Resnick,Sheila Reynolds,Jessica L. Riesterer,Scott J. Rodig,Joseph T. Roland,Sonia Rosenfield,Asaf Rotem,Sudipta Roy,Charles M. Rudin,Marc D. Ryser,Maria Santi-Vicini,Kazuhito Sato,Deborah Schrag,Nikolaus Schultz,Cynthia L. Sears,Rosalie C. Sears,Subrata Sen,Triparna Sen,Alex K. Shalek,Jeff Sheng,Quanhu Sheng,Kooresh I. Shoghi,Martha J. Shrubsole,Yu Shyr,Alexander B. Sibley,Kiara Siex,Alan J. Simmons,Dinah S. Singer,Shamilene Sivagnanam,Michal Slyper,Artem Sokolov,Sheng-Kwei Song,Austin N. Southard-Smith,Avrum Spira,Janet Stein,Phillip B. Storm,Elizabeth H. Stover,Siri H. Strand,Timothy Su,Damir Sudar,Ryan P. Sullivan,Lea F. Surrey,Mario L. Suvà,Nadezhda V. Terekhanova,Luke Ternes,Lisa Thammavong,Guillaume Thibault,George Thomas,Vesteinn Thorsson,Ellen Todres,Linh M. Tran,Madison Tyler,Yasin Uzun,Anil Vachani,Eliezer M. Van Allen,Simon N. Vandekar,Deborah J. Veis,Sébastien Vigneau,Arastoo Vossough,Angela J. Waanders,Nikhil Wagle,Liang-Bo Wang,Michael C. Wendl,Robert B. West,Chi yun Wu,Hao Wu,Hung Yi Wu,Matthew A. Wyczalkowski,Yubin Xie,Xiaolu Yang,Clarence Yapp,Wenbao Yu,Yinyin Yuan,Dadong Zhang,Kun Zhang,Mianlei Zhang,Nan Zhang,Yantian Zhang,Yanyan Zhao,Daniel Cui Zhou,Zilu Zhou,Houxiang Zhu,Qin Zhu,Xiangzhu Zhu,Yuankun Zhu,Xiaowei Zhuang +373 more
TL;DR: The Human Tumor Atlas Network (HTAN), part of the NCI Cancer Moonshot Initiative, will establish a clinical, experimental, computational, and organizational framework to generate informative and accessible three-dimensional atlases of cancer transitions for a diverse set of tumor types.
Journal ArticleDOI
Randomized, placebo-controlled phase II study of vandetanib plus docetaxel in previously treated non-small-cell lung cancer
John V. Heymach,Bruce E. Johnson,Diane Prager,Edit Csada,Jaromír Roubec,Miloš Pešek,Irena Spasova,Chandra P. Belani,Istvan Bodrogi,Shirish Gadgeel,Sarah J. Kennedy,Jeannie Hou,Roy S. Herbst +12 more
TL;DR: In this paper, the authors evaluated the activity of vandetanib plus docetaxel in patients with previously treated non-small-cell lung cancer (NSCLC).