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Bruce E. Johnson
Researcher at Harvard University
Publications - 523
Citations - 76494
Bruce E. Johnson is an academic researcher from Harvard University. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 104, co-authored 474 publications receiving 68801 citations. Previous affiliations of Bruce E. Johnson include University of Adelaide & Virginia Tech.
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Expansion Sequencing: Spatially Precise In Situ Transcriptomics in Intact Biological Systems
Shahar Alon,Shahar Alon,Daniel Goodwin,Anubhav Sinha,Anubhav Sinha,Asmamaw T Wassie,Fei Chen,Evan R. Daugharthy,Evan R. Daugharthy,Yosuke Bando,Atsushi Kajita,Andrew G Xue,Karl Marrett,Robert Prior,Yi Cui,Andrew C. Payne,Chun-Chen Yao,Ho-Jun Suk,Ho-Jun Suk,Ru Wang,Chih-Chieh Yu,Paul W. Tillberg,Paul Reginato,Nikita Pak,Songlei Liu,Songlei Liu,Sukanya Punthambaker,Sukanya Punthambaker,Eswar Prasad Ramachandran Iyer,Richie E. Kohman,Richie E. Kohman,Jeremy A. Miller,Ed S. Lein,Ana Lako,Nicole Cullen,Scott J. Rodig,Karla Helvie,Daniel L Abravanel,Nikhil Wagle,Bruce E. Johnson,Johanna Klughammer,Michal Slyper,Julia Waldman,Judit Jané-Valbuena,Orit Rozenblatt-Rosen,Aviv Regev,Aviv Regev,George M. Church,George M. Church,Adam H. Marblestone,Edward S. Boyden +50 more
TL;DR: Untargeted expansion sequencing (ExSeq) is applied to mouse brain, yielding readout of thousands of genes, including splice variants and novel transcripts, and enables highly multiplexed mapping of RNAs, from nanoscale to system scale.
Journal ArticleDOI
Clinicopathologic features and outcomes of patients with lung adenocarcinomas harboring BRAF mutations in the Lung Cancer Mutation Consortium
Liza C. Villaruz,Mark A. Socinski,Shira Abberbock,Lynne D. Berry,Bruce E. Johnson,David J. Kwiatkowski,A. John Iafrate,Marileila Varella-Garcia,Wilbur A. Franklin,D. Ross Camidge,Lecia V. Sequist,Eric B. Haura,M. Ladanyi,Brenda F. Kurland,Kelly Kugler,John D. Minna,Paul A. Bunn,Mark G. Kris +17 more
TL;DR: The advent of effective targeted therapy for BRAFV600E‐mutant lung adenocarcinomas necessitates further exploration of the unique clinical features and behavior of advanced‐stage BRAF‐mutants lung adeno- carcininomas.
Journal Article
myc Family DNA Amplification in Small Cell Lung Cancer Patients' Tumors and Corresponding Cell Lines
Bruce E. Johnson,Robert W. Makuch,Alfreda D. Simmons,Adi F. Gazdar,David Burch,Alan W. Cashell +5 more
TL;DR: Myc family DNA amplification is present in 16% of small cell lung cancer patients' tumors and the amplification pattern in the tumor cell lines is representative of the fresh tumors obtained from the same patients.
Journal ArticleDOI
A Prospective Evaluation of Circulating Tumor Cells and Cell-Free DNA in EGFR-Mutant Non-Small Cell Lung Cancer Patients Treated with Erlotinib on a Phase II Trial.
Masahiko Yanagita,Amanda J. Redig,Amanda J. Redig,Cloud P. Paweletz,Suzanne E. Dahlberg,Allison O'Connell,Nora Feeney,Myriam Taibi,David Boucher,Geoffrey R. Oxnard,Geoffrey R. Oxnard,Bruce E. Johnson,Bruce E. Johnson,Daniel B. Costa,David M. Jackman,David M. Jackman,Pasi A. Jänne +16 more
TL;DR: Circulating tumor cell (CTC) or cell-free DNA (cfDNA) analysis may allow for noninvasive evaluation of acquired resistance to first-line EGFR TKIs and may expand the number of patients in whom actionable genetic information can be obtained at acquired resistance.
Journal Article
The new IASLC/ATS/ERS international multidisciplinary lung adenocarcinoma classification
William D. Travis,Elisabeth Brambilla,Masayuki Noguchi,Kim R. Geisinger,David G. Beer,Charles A. Powell,Bruce E. Johnson,Gregory J. Riely,Valerie W. Rusch,Hisao Asamura,Kavita Garg,John H. M. Austin,Denise R. Aberle,Christian Brambilla,Douglas B. Flieder,Wilbur A. Franklin,Adi F. Gazdar,Michael K. Gould,Philip S. Hasleton,Douglas W. Henderson,Fred R. Hirsch,Rudolf M. Huber,Yuichi Ishikawa,James R. Jett,Keith M. Kerr,David W. Johnson,Keiko Kuriyama,Jin Soo Lee,Vincent A. Miller,Tetsuya Mitsudomi,Andrew G. Nicholson,Iver Petersen,Victor L. Roggli,Rafael Rosell,Nagahiro Saijo,Montserrat Sanchez-Cespedes,Giorgio V. Scagliotti,Jean-Paul Sculier,Takashi Takahashi,Erik Thunnissen,M. Tsao,Masahiro Tsuboi,Paul Van Schil,Johan Vansteenkiste,Yasushi Yatabe,Ignacio I. Wistuba,Pan-Chyr Ynag +46 more