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Bruce J. Holub
Researcher at University of Guelph
Publications - 185
Citations - 9048
Bruce J. Holub is an academic researcher from University of Guelph. The author has contributed to research in topics: Eicosapentaenoic acid & Docosahexaenoic acid. The author has an hindex of 49, co-authored 184 publications receiving 8718 citations. Previous affiliations of Bruce J. Holub include Pennsylvania State University & St. Joseph's Hospital and Medical Center.
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"Essential fatty acids" in aquatic ecosystems: a crucial link between diet and human health and evolution
TL;DR: The marine FA synthesis/transport cycle and traditional and nontraditional sources of EFA are reviewed and it is suggested that, while some traditional sources of marine oils are in steady decline, other sources hold great promise for maintaining access to EFA.
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n−3 Fatty acids and cardiovascular disease risk factors among the Inuit of Nunavik
Eric Dewailly,Carole Blanchet,Simone Lemieux,Louise Sauvé,Suzanne Gingras,Pierre Ayotte,Bruce J. Holub +6 more
TL;DR: The traditional Inuit diet, which is rich in n-3 fatty acids, is probably responsible for the low mortality rate from ischemic heart disease in this population, and appears to beneficially affect some cardiovascular disease risk factors.
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Supplementation with Quercetin Markedly Increases Plasma Quercetin Concentration without Effect on Selected Risk Factors for Heart Disease in Healthy Subjects
Julie A. Conquer,Giuseppe Maiani,Giuseppe Maiani,Elena Azzini,Elena Azzini,A. Raguzzini,A. Raguzzini,Bruce J. Holub +7 more
TL;DR: Adding a quercetin-containing supplement to the diet markedly enhanced the plasma quercETin concentration but had no effect on other cardiovascular or thrombogenic risk factors.
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Anthocyanin metabolites in human urine and serum
TL;DR: It is confirmed that human subjects have the capacity to metabolise cyanidin 3-glycosides, as at least ten individual anthocyanin metabolites in the urine and serum, and these metabolic products are likely in part responsible for the reported health benefits associated with the consumption of Anthocyanins.
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Supplementation with an algae source of docosahexaenoic acid increases (n-3) fatty acid status and alters selected risk factors for heart disease in vegetarian subjects
Julie A. Conquer,Bruce J. Holub +1 more
TL;DR: DHA supplementation markedly enhanced the DHA status (of serum and platelets), provided for the formation of substantial EPA, and lowered the total and LDL-cholesterol:HDL-ch cholesterol ratios.