B
Bruno Polak
Researcher at Max Planck Society
Publications - 4
Citations - 278
Bruno Polak is an academic researcher from Max Planck Society. The author has contributed to research in topics: Spindle apparatus & Kinetochore. The author has an hindex of 3, co-authored 4 publications receiving 219 citations.
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Journal ArticleDOI
Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
Janko Kajtez,Anastasia Solomatina,Maja Novak,Bruno Polak,Kruno Vukušić,Jonas Rudiger,Gheorge Cojoc,Ana Milas,Ivana Šumanovac Šestak,Patrik Risteski,Federica Tavano,Anna H. Klemm,Emanuele Roscioli,Emanuele Roscioli,Emanuele Roscioli,Julie P.I. Welburn,Daniela Cimini,Daniela Cimini,Matko Glunčić,Nenad Pavin,Iva M. Tolić +20 more
TL;DR: It is concluded that the bridging fibre, by linking sister k-fibres, withstands the tension between sister kinetochores and enables the spindle to obtain a curved shape.
Journal ArticleDOI
PRC1‐labeled microtubule bundles and kinetochore pairs show one‐to‐one association in metaphase
TL;DR: It is shown that in a metaphase spindle more than 90% of overlap bundles act as a bridge between sister k‐fibers, suggesting a function of PRC1 in bridging microtubule organization and force balance in the metaphases spindle.
Journal ArticleDOI
The mitotic spindle is chiral due to torques within microtubule bundles.
Maja Novak,Bruno Polak,Juraj Simunić,Zvonimir Boban,Barbara Kuzmić,Andreas W. Thomae,Iva M. Tolić,Nenad Pavin +7 more
TL;DR: The authors find that in addition to forces, torques caused by the microtubule motor protein kinesin-5 induce chirality and curves into the spindle and determine its chiral architecture.
Posted ContentDOI
The mitotic spindle is chiral due to torques generated by motor proteins
Maja Novak,Bruno Polak,Juraj Simunić,Zvonimir Boban,Barbara Kuzmić,Andreas W. Thomae,Iva M. Tolić,Nenad Pavin +7 more
TL;DR: It is concluded that torques generated by motor proteins, in addition to forces, exist in the spindle and determine its architecture, and it is shown that torque is required to generate the helical shapes.