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Bruno Sposato
Researcher at University of Rome Tor Vergata
Publications - 67
Citations - 797
Bruno Sposato is an academic researcher from University of Rome Tor Vergata. The author has contributed to research in topics: Asthma & FEV1/FVC ratio. The author has an hindex of 14, co-authored 58 publications receiving 666 citations. Previous affiliations of Bruno Sposato include Sapienza University of Rome.
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Pulmonary alveolar microlithiasis: report on 576 cases published in the literature.
TL;DR: This review of PAM has shown that the etiology of the disease is still unknown, it is widespread throughout the world and easy to diagnose; it develops slowly and therapy is ineffective except for lung transplantation.
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Asthma control in elderly asthmatics. An Italian observational study
Manlio Milanese,F. Di Marco,Angelo Corsico,Giovanni Rolla,Bruno Sposato,Fulvia Chieco-Bianchi,Maria Teresa Costantino,Mariangiola Crivellaro,Gabriella Guarnieri,Nicola Scichilone +9 more
TL;DR: The results highlight the need to specifically evaluate the coexistence of features of COPD in elderly asthmatics, a factor that worsens asthma control.
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Mepolizumab effectiveness on small airway obstruction, corticosteroid sparing and maintenance therapy step-down in real life.
Bruno Sposato,Gianna Camiciottoli,Elena Bacci,Marco Scalese,Giovanna Elisiana Carpagnano,Corrado Pelaia,Pierachille Santus,Mauro Maniscalco,Simonetta Masieri,Angelo Corsico,Nicola Scichilone,Stefano Baglioni,Nicola Murgia,Ilenia Folletti,Giulio Bardi,Amelia Grosso,Paolo Cameli,Manuela Latorre,Antonino Musarra,Elena Bargagli,Alberto Ricci,Girolamo Pelaia,Pierluigi Paggiaro,Paola Rogliani +23 more
TL;DR: In real-life, MEP improved significantly all outcomes even small airway obstruction, suggesting its possible role also in distal lung region treatment.
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Factors reducing omalizumab response in severe asthma.
Bruno Sposato,Marco Scalese,Manlio Milanese,Simonetta Masieri,Carlo Cavaliere,Manuela Latorre,Nicola Scichilone,Andrea Matucci,Alessandra Vultaggio,Alberto Ricci,Alberto Cresti,Pierachille Santus,Antonio Perrella,Pierluigi Paggiaro +13 more
TL;DR: Age, obesity, comorbidities, smoking habits, nasal polyps, allergic poly-sensitization might reduce Omalizumab effectiveness independently to other asthma-influencing factors.
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Effects of omalizumab in severe asthmatics across ages: A real life Italian experience
Bruno Sposato,Marco Scalese,Manuela Latorre,Nicola Scichilone,Andrea Matucci,Manlio Milanese,Simonetta Masieri,Giovanni Rolla,G. Steinhilber,Y. Rosati,Alessandra Vultaggio,Ilenia Folletti,Stefano Baglioni,Elena Bargagli,M. Di Tomassi,R. Pio,A. Pio,Uberto Maccari,Claudia Maggiorelli,Maria Giovanna Migliorini,L. Vignale,N. Pulerà,Giovanna Elisiana Carpagnano,M. P. Foschino Barbaro,Antonio Perrella,Pierluigi Paggiaro +25 more
TL;DR: Omalizumab improves all asthma outcomes independently of age, although the magnitude of the effects observed in the elderly seems to be lower than in the other age groups.