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Bryan W. Clark
Researcher at United States Environmental Protection Agency
Publications - 28
Citations - 2176
Bryan W. Clark is an academic researcher from United States Environmental Protection Agency. The author has contributed to research in topics: Killifish & Population. The author has an hindex of 15, co-authored 27 publications receiving 1858 citations. Previous affiliations of Bryan W. Clark include Iowa State University & Duke University.
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Journal ArticleDOI
The toxicology of climate change: environmental contaminants in a warming world.
Pamela D. Noyes,Matthew K. McElwee,Hilary D. Miller,Bryan W. Clark,Lindsey A. Van Tiem,Kia C.E. Walcott,Kyle N. Erwin,Edward D. Levin +7 more
TL;DR: A paramount issue will be to identify species and populations especially vulnerable to climate-pollutant interactions, in the context of the many other physical, chemical, and biological stressors that will be altered with climate change.
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The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish.
Noah M. Reid,Dina A. Proestou,Bryan W. Clark,Wesley C. Warren,John K. Colbourne,Joseph R. Shaw,Joseph R. Shaw,Sibel I. Karchner,Sibel I. Karchner,Mark E. Hahn,Mark E. Hahn,Diane Nacci,Marjorie F. Oleksiak,Douglas L. Crawford,Andrew Whitehead +14 more
TL;DR: High genetic diversity in killifish seems to allow selection to act on existing variation, driving rapid adaptation to selective forces such as pollution, and the aryl hydrocarbon receptor–based signaling pathway is identified as a shared target of selection.
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Environmental Fate and Effects of Bacillus thuringiensis (Bt) Proteins from Transgenic Crops: a Review
TL;DR: Assessment of the nontarget effects of Bt protein toxins indicates that there is a low level of hazard to most groups of nontarget organisms, although some investigations are of limited ecological relevance.
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AHR2 mediates cardiac teratogenesis of polycyclic aromatic hydrocarbons and PCB-126 in Atlantic killifish (Fundulus heteroclitus).
TL;DR: It is demonstrated that A HR2 is the primary mediator of cardiac teratogenesis caused by multiple aryl hydrocarbons in Fundulus and suggested that suppression of the AHR pathway through modulation of AHR2 is a plausible mechanism for PAH resistance in adapted fish.
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When evolution is the solution to pollution: Key principles, and lessons from rapid repeated adaptation of killifish (Fundulus heteroclitus) populations.
TL;DR: How selection by industrial pollutants and other stressors has acted on multiple populations of killifish is described and it is posited that extreme nucleotide diversity uniquely positions this species for successful evolutionary adaptation.