B
Brygida Berse
Researcher at Harvard University
Publications - 26
Citations - 10112
Brygida Berse is an academic researcher from Harvard University. The author has contributed to research in topics: Vascular endothelial growth factor & Vascular endothelial growth factor A. The author has an hindex of 22, co-authored 26 publications receiving 9940 citations. Previous affiliations of Brygida Berse include Beth Israel Deaconess Medical Center & Veterans Health Administration.
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Journal ArticleDOI
Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors
TL;DR: Evidence is presented that the VPF/VEGF gene is expressed in many adult organs, including lung, kidney, adrenal gland, heart, liver, and stomach mucosa, as well as in elicited peritoneal macrophages and in human tumors, where it may be involved in promoting tumor angiogenesis and stroma generation.
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Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing.
Lawrence F. Brown,Kiang-Teck Yeo,Brygida Berse,Tet-Kin Yeo,Donald R. Senger,Harold F. Dvorak,L Van de Water +6 more
TL;DR: Evidence is presented indicating that vascular permeability factor (VPF; also known as vascular endothelial growth factor) may be responsible for the hyperpermeable state, as well as the angiogenesis, that are characteristic of healing wounds, and that VPF is an important cytokine in wound healing.
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Vascular permeability factor (VPF, VEGF) in tumor biology
Donald R. Senger,L Van de Water,Lawrence F. Brown,Janice A. Nagy,Kiang-Teck J. Yeo,Tet-Kin Yeo,Brygida Berse,Robert W. Jackman,Ann M. Dvorak,Harold F. Dvorak +9 more
TL;DR: VPF/VEGF has recently been found to have a role in wound healing and its expression by activated macrophages suggests that it probably also participates in certain types of chronic inflammation.
Journal Article
Expression of Vascular Permeability Factor (Vascular Endothelial Growth Factor) and Its Receptors in Adenocarcinomas of the Gastrointestinal Tract
Lawrence F. Brown,Brygida Berse,Robert W. Jackman,Kathi Tognazzi,Eleanor J. Manseau,Donald R. Senger,Harold F. Dvorak +6 more
TL;DR: Data indicate that primary autochthonous human tumors of gastrointestinal origin regularly express both VPF mRNA and VPF protein and that adjacent stromal vessels express mRNAs for both known VPF receptors.
Journal Article
Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model.
Joan W. Miller,Anthony P. Adamis,David T. Shima,Patricia A. D'Amore,Rachel S. Moulton,Michael S. O'Reilly,Judah Folkman,Harold F. Dvorak,Lawrence F. Brown,Brygida Berse,Tet Kin Yeo,Kiang-Teck J. Yeo +11 more
TL;DR: In this article, the authors investigated the association of VEGF with the development of experimental iris neovascularization in the cynomolgus monkey and found that the aqueous vascular endothelial growth factor/vascular permeability factor (VEGF) levels changed synchronously and proportionally with the severity of intraocular iris lesion.