Burhan Gharaibeh

TL;DR: Myoendothelial cells regenerate myofibers in the injured skeletal muscle of severe combined immunodeficiency mice more effectively than CD56+ myogenic progenitors, are amenable to biotechnological handling, including purification by flow cytometry and long-term expansion in vitro, and may have potential for the treatment of human muscle disease.

TL;DR: This protocol details a procedure, known as the modified preplate technique, which is currently used in the laboratory to isolate muscle cells on the basis of selective adhesion to collagen-coated tissue culture plates to isolate RAC and SAC populations from murine skeletal muscle.

TL;DR: Results indicate that some of the chromosomal instability observed within these cancer cells might be the result of cytoskeletal defects and breakage-fusion-bridge cycles.

TL;DR: It is shown here that cell sex is a variable that considerably influences MDSCs' regeneration abilities and should persuade researchers to report cell sex, which is a largely unexplored variable, and consider the implications of relying on cells of one sex.

TL;DR: The results demonstrate that MDSC-based therapy involving sFlt-1 and BMP-4 repairs articular cartilage in OA mainly by having a beneficial effect on chondrogenesis by the donor and host cells as well as by preventing angiogenesis, which eventually prevents cartilage resorption, resulting in persistent cartilage regeneration and repair.