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Bin Sun
Researcher at University of Pittsburgh
Publications - 12
Citations - 5217
Bin Sun is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Skeletal muscle & Stem cell. The author has an hindex of 12, co-authored 12 publications receiving 4845 citations. Previous affiliations of Bin Sun include Boston Children's Hospital.
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Journal ArticleDOI
A perivascular origin for mesenchymal stem cells in multiple human organs
Mihaela Crisan,Solomon Yap,Louis Casteilla,Louis Casteilla,Chien Wen Chen,Mirko Corselli,Tea Soon Park,Gabriella Andriolo,Bin Sun,Bo Zheng,Li Zhang,Cyrille Norotte,Pang-ning Teng,Jeremy Traas,Rebecca C. Schugar,Bridget M. Deasy,Stephen F. Badylak,Hans-Jörg Bühring,Jean-Paul Giacobino,Lorenza Lazzari,Johnny Huard,Bruno Péault +21 more
TL;DR: Blood vessel walls harbor a reserve of progenitor cells that may be integral to the origin of the elusive MSCs and other related adult stem cells.
Journal ArticleDOI
The Tunica Adventitia of Human Arteries and Veins As a Source of Mesenchymal Stem Cells
TL;DR: This work demonstrates the co-existence of 2 separate perivascular MSC progenitors: pericytes in capillaries and microvessels and adventitial cells around larger vessels.
Journal ArticleDOI
Prospective identification of myogenic endothelial cells in human skeletal muscle
Bo Zheng,Baohong Cao,Mihaela Crisan,Bin Sun,Guangheng Li,Alison J. Logar,Solomon Yap,Jonathan B. Pollett,Lauren Drowley,Theresa Cassino,Burhan Gharaibeh,Bridget M. Deasy,Johnny Huard,Bruno Péault +13 more
TL;DR: Myoendothelial cells regenerate myofibers in the injured skeletal muscle of severe combined immunodeficiency mice more effectively than CD56+ myogenic progenitors, are amenable to biotechnological handling, including purification by flow cytometry and long-term expansion in vitro, and may have potential for the treatment of human muscle disease.
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A role for cell sex in stem cell–mediated skeletal muscle regeneration: female cells have higher muscle regeneration efficiency
Bridget M. Deasy,Aiping Lu,Jessica C. Tebbets,Joseph M. Feduska,Rebecca C. Schugar,Jonathan B. Pollett,Bin Sun,Kenneth L. Urish,Burhan Gharaibeh,Baohong Cao,Robert T. Rubin,Johnny Huard +11 more
TL;DR: It is shown here that cell sex is a variable that considerably influences MDSCs' regeneration abilities and should persuade researchers to report cell sex, which is a largely unexplored variable, and consider the implications of relying on cells of one sex.
Journal ArticleDOI
A Reservoir of Brown Adipocyte Progenitors in Human Skeletal Muscle
Mihaela Crisan,Louis Casteilla,Louis Casteilla,Lorenz Lehr,Mamen Carmona,Ariane Paoloni-Giacobino,Solomon Yap,Bin Sun,Bertrand Léger,Alison J. Logar,Luc Pénicaud,Patrick Schrauwen,David Cameron-Smith,Aaron P. Russell,Bruno Péault,Jean-Paul Giacobino +15 more
TL;DR: The existence in human skeletal muscle and the prospective isolation of progenitor cells with a high potential for UCP1 expression are shown for the first time and the discovery of this reservoir generates a new hope of treating obesity by acting on energy dissipation.