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Byron D. Ford
Researcher at University of California, Riverside
Publications - 66
Citations - 2105
Byron D. Ford is an academic researcher from University of California, Riverside. The author has contributed to research in topics: Neuroprotection & Neuregulin 1. The author has an hindex of 25, co-authored 65 publications receiving 1851 citations. Previous affiliations of Byron D. Ford include National Institutes of Health & Morehouse School of Medicine.
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Journal ArticleDOI
Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agent- induced delayed neuronal injury
Yonggang Li,Pamela J. Lein,Gregory D. Ford,Cuimei Liu,Cuimei Liu,Kyndra C. Stovall,Kyndra C. Stovall,Kyndra C. Stovall,Todd E. White,Donald A. Bruun,Teclemichael Tewolde,Alicia Gates,Timothy J. Distel,Monique C. Surles-Zeigler,Byron D. Ford +14 more
TL;DR: Neuroprotection by NRG-1 against OP neurotoxicity is associated with the suppression of pro-inflammatory responses in brain microglia, and these findings provide new insight regarding the molecular mechanisms involved in the neuroprotective role of NRg-1 in acute brain injuries.
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Spontaneous Isomerization of Long-Lived Proteins Provides a Molecular Mechanism for the Lysosomal Failure Observed in Alzheimer's Disease.
Tyler R. Lambeth,Dylan L. Riggs,Lance E. Talbert,Jin Tang,Emily Coburn,Amrik S. Kang,Jessica Noll,Catherine Augello,Byron D. Ford,Ryan R. Julian +9 more
TL;DR: Spontaneous chemistry can provide modified substrates capable of inducing gradual lysosomal failure, which may play an important role in the cascade of events leading to the disrupted proteostasis, amyloid formation, and tauopathies associated with AD.
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Neuroprotective effects of neuregulin-1 on B35 neuronal cells following ischemia.
DaJoie R. Croslan,Matthew C. Schoell,Gregory D. Ford,John V.K. Pulliam,Alicia Gates,Ceilessia M. Clement,Adalynn E. Harris,Byron D. Ford +7 more
TL;DR: An in vitro rat ischemia model is developed to gain insight into the mechanisms employed by NRG-1 to protect neurons from ischemic brain injury and is prevented by an inhibitor of the phosphatidylinositol-3-kinase/Akt pathway.
Journal ArticleDOI
Neuregulin-1 is Neuroprotective in a Rat Model of Organophosphate-Induced Delayed Neuronal Injury
Yonggang Li,Pamela J. Lein,Cuimei Liu,Donald A. Bruun,Cecilia R Giulivi,Gregory D. Ford,Gregory D. Ford,Teclemichael Tewolde,Catherine Ross-Inta,Byron D. Ford +9 more
TL;DR: NRG-1 is identified as a promising adjuvant therapy to current medical countermeasures for enhancing neuroprotection against acute OP intoxication and blocked apoptosis and oxidative stress-mediated protein damage in the brains of DFP-intoxicated rats.
Journal ArticleDOI
Chronic ethanol ingestion produces cholinergic hypofunction in rat brain
Eric A. Floyd,Eric A. Floyd,A.C. Young-Seigler,Byron D. Ford,Jonathan D. Reasor,E.L. Moore,James G. Townsel,H.K. Rucker +7 more
TL;DR: The results indicate a neurotoxic effect of prolonged intake of ethanol on the basal forebrain cholinergic projection system, which may cause impairment ofCholinergic innervation of target areas of the basal nucleus complex.