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C. A. G. Haasnoot
Researcher at Leiden University
Publications - 9
Citations - 982
C. A. G. Haasnoot is an academic researcher from Leiden University. The author has contributed to research in topics: Pseudorotation & Proton NMR. The author has an hindex of 8, co-authored 9 publications receiving 960 citations.
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Prediction of anti and gauche vicinal proton‐proton coupling constants in carbohydrates: A simple additivity rule for pyranose rings
TL;DR: In this article, a set of parameters were used to calculate 3J(HH) coupling constants in a variety of pyranosides and related compounds and a comparison with experimental values taken from the literature showed that couplings in molecules which are conformationally pure and underformed can be predicted with a surprising accuracy.
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Empirical Correlations Between Conformational Parameters in β‐D‐Furanoside Fragments Derived from a Statistical Survey of Crystal Structures of Nucleic Acid Constituents Full Description of Nucleoside Molecular Geometries in Terms of Four Parameters
TL;DR: In this article, a data file was created containing internal coordinates and derived parameters for 178 β-D-furanoside fragments, occurring in X-ray structures of ribo-, 2′-deoxyribo- and arabinonucleoside derivatives.
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The relationship between proton–proton NMR coupling constants and substituent electronegativities. II—conformational analysis of the sugar ring in nucleosides and nucleotides in solution using a generalized Karplus equation
TL;DR: The relationship between NMR proton-proton coupling constants and pseudorotational properties of the sugar ring in nucleosides and nucleotides is investigated in this paper, where a new empirical generalization of the classical Karplus equation is utilized, which allows an accurate correction for the effects of electronegativity and orientation of substituents on 3J(HH).
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Relationship between proton–proton nmr coupling constants and substituent electronegativities. III. Conformational analysis of proline rings in solution using a generalized Karplus equation
TL;DR: In this article, the relationship between published vicinal proton-proton coupling constants and pseudorotation properties of the pyrrolidine ring in L-proline, 4-hydroxy-Lproline and cyclic model proline peptides is investigated, and the best fit of the conformational parameters to the experimental coupling constants is obtained by means of a computerized iterative least squares procedure.
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Complete assignment and conformational analysis of a deoxyribotetranucleotide. d(TAAT). A 360 and 500 Mhz NMR study.
TL;DR: A proton NMR study was carried out on the tetranucleoside triphosphate d(TAAT) at a temperature of 27 degrees C and it is concluded that the central -dA(2)- dA(3)- part of the molecule occurs preferentially as a mixture of two right-handed single-helical conformations, denoted S-S and S-N.