C
C. Sinha
Researcher at Indian Institute of Toxicology Research
Publications - 7
Citations - 277
C. Sinha is an academic researcher from Indian Institute of Toxicology Research. The author has contributed to research in topics: Tyrosine hydroxylase & Dopaminergic. The author has an hindex of 6, co-authored 7 publications receiving 260 citations.
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Journal ArticleDOI
Neuroprotective and neurorescue effect of black tea extract in 6-hydroxydopamine-lesioned rat model of Parkinson's disease.
Rajnish Kumar Chaturvedi,S. Shukla,Kavita Seth,S. Chauhan,C. Sinha,Yogeshwer Shukla,Ashok K. Agrawal +6 more
TL;DR: Results suggest that BTE exerts both neuroprotective and neurorescue effects against 6-OHDA-induced degeneration of the nigrostriatal dopaminergic system, suggesting that possibly daily intake of BTE may slow down the PD progression as well as delay the onset of neurodegenerative processes in PD.
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Mosquito repellent (pyrethroid-based) induced dysfunction of blood-brain barrier permeability in developing brain.
C. Sinha,Ashok K. Agrawal,Fakhrul Islam,Kavita Seth,Rajnish Kumar Chaturvedi,S. Shukla,Prahlad K. Seth +6 more
TL;DR: Pyrethroid‐based mosquito repellents (MR) are commonly used to protect humans against mosquito vector and the neurotoxicity caused by MR has aroused concern among public regarding their use.
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Behavioral and neurochemical effects induced by pyrethroid-based mosquito repellent exposure in rat offsprings during prenatal and early postnatal period.
C. Sinha,Kavita Seth,Fakhrul Islam,Rajnish Kumar Chaturvedi,S. Shukla,Neeraj Mathur,N. Srivastava,Ashok K. Agrawal +7 more
TL;DR: The result suggests that pyrethroid-based MR inhalation during early developmental period may have adverse effect on developing nervous system causing cholinergic dysfunction leading to learning and memory deficit.
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Effect of glial cell line-derived neurotrophic factor (GDNF) co-transplantation with fetal ventral mesencephalic cells (VMC) on functional restoration in 6-hydroxydopamine (6-OHDA) lesioned rat model of Parkinson's disease: neurobehavioral, neurochemical and immunohistochemical studies.
Rajnish Kumar Chaturvedi,Ashok K. Agrawal,Kavita Seth,S. Shukla,S. Chauhan,Yogeshwer Shukla,C. Sinha,Prahlad K. Seth +7 more
TL;DR: Results suggest that co‐transplantation of VMC and GDNF may be a better approach towards functional restoration in 6‐OHDA lesioned rat model of Parkinson's disease.
Journal ArticleDOI
Co-transplantation of carotid body and ventral mesencephalic cells as an alternative approach towards functional restoration in 6-hydroxydopamine-lesioned rats: implications for Parkinson's disease.
S. Shukla,Ashok K. Agrawal,Rajnish Kumar Chaturvedi,Kavita Seth,Nalini Srivastava,C. Sinha,Yogeshwer Shukla,Vinay K. Khanna,Prahlad K. Seth +8 more
TL;DR: The result suggests that co‐transplantation of CB cells along with VMC provides better and long‐term functional restoration in the rat model of PD, possibly by supporting the survival of newly grafted cells as well as remaining host DA neurons.