S. Shukla

TL;DR: Findings show that impaired function of PGC-1alpha plays a critical role in muscle dysfunction in Huntington's disease, and that treatment with agents to enhance P GC-1 alpha function could exert therapeutic benefits, and muscle may provide a readily accessible tissue in which to monitor therapeutic interventions.

TL;DR: Results suggest that BTE exerts both neuroprotective and neurorescue effects against 6-OHDA-induced degeneration of the nigrostriatal dopaminergic system, suggesting that possibly daily intake of BTE may slow down the PD progression as well as delay the onset of neurodegenerative processes in PD.

TL;DR: Cotransplantation of OECs and VMC may be a better approach for functional restoration in 6-OHDA-induced rat model of Parkinson's disease, which was assessed using neurobehavioral, neurochemical, and immunohistochemical approach.

TL;DR: Pyrethroid‐based mosquito repellents (MR) are commonly used to protect humans against mosquito vector and the neurotoxicity caused by MR has aroused concern among public regarding their use.

TL;DR: The results suggest that NGF at the time of transplantation exhibits neuroprotective effect on transplanted VMC as well as neurorescue effect on remaining host nigral dopaminergic neurons, leading to better functional restoration.