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C T De Rosa

Researcher at U.S. Agency for Toxic Substances and Disease Registry

Publications -  20
Citations -  682

C T De Rosa is an academic researcher from U.S. Agency for Toxic Substances and Disease Registry. The author has contributed to research in topics: Environmental exposure & Risk assessment. The author has an hindex of 13, co-authored 20 publications receiving 638 citations. Previous affiliations of C T De Rosa include United States Department of Health and Human Services.

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Animals as sentinels of human health hazards of environmental chemicals.

TL;DR: Although it is unlikely that sentinel species data will be used as the sole determinative factor in evaluating human health concerns, such data can be useful as for additional weight of evidence in a risk assessment, for providing early warning of situations requiring further study, or for monitoring the course of remedial activities.
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Implications of chemical mixtures in public health practice

TL;DR: The need for studies on chemical mixtures has been proposed as one of the six priority areas the agency identified in its agenda for public health environmental research.
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Public health implications of hazardous waste sites: findings, assessment and research.

TL;DR: An overview of the chemicals released from hazardous waste sites and some of the mixtures of substances that have been released into environmental media is presented and the utility of this information in the context of risk analysis and public health practice is discussed.
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Prediction of the health effects of polychlorinated biphenyls (PCBs) and their metabolites using quantitative structure-activity relationship (QSAR).

TL;DR: The hypothesis that environmental exposure to some PCBs and/ or their metabolites could produce mutagenicity and/or carcinogenicity is supported, and these data should be considered as priority toxicological testing data needs.
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Gene induction studies and toxicity of chemical mixtures

TL;DR: Two studies with techniques that are being used increasingly in experimental toxicology provide insights into complex interactions that occur in cellular systems and could be used to identify biomarkers of exposure to other environmental chemical mixtures.