Caitlin Campbell

TL;DR: This report describes a novel long noncoding RNA that is induced by cigarette smoke extract both in vitro and in vivo and is elevated in numerous lung cancer cell lines, and identifies a novel and intriguing new nonc coding RNA that may act downstream of NRF2 to regulate gene expression and mediate oxidative stress protection in airway epithelial cells.

TL;DR: All carbohydrate-supplement types were equally effective in maintaining blood glucose levels during exercise and improving exercise performance compared with water only and there were no significant differences in blood glucose between carbohydrate treatments.

TL;DR: Despite improved fitness and blood sugar control, indices of incomplete mitochondrial FAO increased in a similar manner in response to a fixed load acute exercise bout, indicating that intramitochondrial muscle FAO is inherently inefficient and is tethered directly to ATP turnover.

TL;DR: The results support a working model in which improved metabolic health modifies host metabolism in parallel with altering systemic exposure to xeno-metabolites, and highlight that interpretations regarding the origins of peripheral blood or urinary “signatures” of insulin resistance and metabolic health must consider the potentially important contribution of gut-derived metabolites toward the host's metabolome.

TL;DR: The principle that most metabolic changes during sub-maximal aerobic exercise are closely tethered to absolute ATP turnover rate (workload), regardless of fitness or metabolic health status is supported.