Caitriona M. O'Driscoll

TL;DR: In this article , the relationship between the gut microbiota and the integrity of the blood-cerebrospinal fluid barrier was assessed using confocal microscopy, which is localized to the choroid plexus epithelium.

TL;DR: A review of preclinical models of acute myeloid leukemia (AML) can be found in this article , where the authors provide a state-of-the-art overview on the different pre-clinical models available to expand insights into disease pathology and as preclinical screening tools.

TL;DR: Estimation of the stability of amphiphilic cyclodextrin-based nanoparticles containing insulin glulisine indicated that potential exists for further development of the formulation to simultaneously achieve prolonged stability and therapeutic efficacy.

TL;DR: An overview of the state-of-the-art in lipid-based nanoparticles (LNP) technology is provided in this article , focusing on the delivery of a range of nucleic acids, with a particular emphasis on the rationale behind the design of LNPs and attempts to elucidate the resulting molecular assembly and structure, their interactions with cellular proteins and biodistribution.

TL;DR: In this article, a macrocyclic derivative which is formed by modification of a macrocycle is defined, which includes bilayer vesicles, micelles, monolayers, nanoparticles, colloidal assemblies and surface-coated assemblies.