Cameron Gilbert

TL;DR: There is no evidence of an increased risk for major malformations when metformin is taken during the first trimester of pregnancy, on the basis of the limited data available today.

TL;DR: The pathophysiology of cobalt toxicity in patients with metal-on-metal hip arthroplasties is highlighted and patients with new or evolving hip symptoms with a prior history of THA warrant orthopaedic surgical evaluation.

TL;DR: There are many safe treatment options for the clinician when dealing with allergic rhinitis during pregnancy, and recommendations should be based both on the safety of the drugs during pregnancy and the comparative efficacy of the agent in the treatment of the underlying condition.

TL;DR: The purpose of this review is to examine the use of cobalt alloys in total hip arthroplasty, to review the methods of measuring circulating cobalt levels, to define a level of Cobalt which is considered pathological and to Review the pathophysiology, risk factors and treatment of cobALT toxicity.

TL;DR: A man presented with hypothyroidism, dilated cardiomyopathy, a pericardial effusion, liver failure, and polycythaemia, and given his acutely profound illness and constellation of symptoms, a diagnosis of cobalt toxicity was made.