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Camille Dumont

Researcher at Claude Bernard University Lyon 1

Publications -  7
Citations -  150

Camille Dumont is an academic researcher from Claude Bernard University Lyon 1. The author has contributed to research in topics: Solid lipid nanoparticle & Nanocarriers. The author has an hindex of 4, co-authored 5 publications receiving 97 citations. Previous affiliations of Camille Dumont include University of Lyon.

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Journal ArticleDOI

Lipid-based nanosuspensions for oral delivery of peptides, a critical review

TL;DR: Different techniques used to produce SLN and NLC with potential or effective peptide encapsulation are outlined and basic principles of covalent and non-covalent lipidization are described and discussed as a prerequisite to improve hydrophilic peptides encapsulation in lipid-based nanosuspensions.
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Development of self emulsifying lipid formulations of BCS class II drugs with low to medium lipophilicity.

TL;DR: The potential of surfactant-based formulations - i.e., Type IV systems from the lipid formulation classification system - for this type of hydrophobic drug is demonstrated.
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In-vitro evaluation of solid lipid nanoparticles: Ability to encapsulate, release and ensure effective protection of peptides in the gastrointestinal tract

TL;DR: Despite an increased amount of encapsulated peptide in solid lipid-based nanoparticles following HIP formation, the important specific surface area linked to their platelet structures resulted in an important peptide release upon dispersion in FaSSIF-V2 and limited protection towards enzymatic degradation.
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A proof-of-concept for developing oral lipidized peptide Nanostructured Lipid Carrier formulations

TL;DR: In this paper, the authors developed a protocol to encapsulate lipidized-peptides in Nanostructured Lipid Carrier (NLC) by High Pressure Homogenization (HPH) for oral delivery.
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Solid lipid nanocarriers diffuse effectively through mucus and enter intestinal cells - but where is my peptide?

TL;DR: Improvement of peptide lipidization should maintain encapsulation and enable benefit from nanocarriers enhanced intestinal transport to improve peptide transport across the intestinal border.