V
Vincent Jannin
Researcher at University of Paris-Sud
Publications - 77
Citations - 3755
Vincent Jannin is an academic researcher from University of Paris-Sud. The author has contributed to research in topics: Drug delivery & Glyceryl behenate. The author has an hindex of 32, co-authored 75 publications receiving 2952 citations.
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Approaches for the development of solid and semi-solid lipid-based formulations☆
TL;DR: The aim of this review is to present the recent approaches in selecting the most appropriate lipid system(s); methods for characterization of their behavior in vitro and in vivo; and the current formulation and processing techniques to obtain various solid dosage forms.
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Toward the establishment of standardized in vitro tests for lipid‐based formulations, part 1: Method parameterization and comparison of in vitro digestion profiles across a range of representative formulations
Hywel David Williams,Philip Jonas Sassene,Karen Kleberg,Jean-Claude Bakala-N'Goma,Marilyn Calderone,Vincent Jannin,Annabel Igonin,Anette Partheil,Delphine Marchaud,Eduardo Jule,Jan Vertommen,Mario Maio,Ross Blundell,Hassan Benameur,Frédéric Carrière,Anette Müllertz,Christopher J.H. Porter,Colin W. Pouton +17 more
TL;DR: In this article, baseline conditions for the conduct of digestion tests are suggested and a series of eight model LBFs are described to probe test performance across different formulation types. Digestion experiments were performed in vitro using a pHstat apparatus and danazol employed as a model poorly water-soluble drug.
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Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems
Ben J. Boyd,Christel A. S. Bergström,Zahari Vinarov,Martin Kuentz,Joachim Brouwers,Patrick Augustijns,Martin Brandl,Andreas Bernkop-Schnürch,Neha Shrestha,Véronique Préat,Anette Müllertz,Annette Bauer-Brandl,Vincent Jannin +12 more
TL;DR: The challenge presented by these drugs is defined, contemporary strategies to solve this challenge are outlined, and consequent in silico and in vitro evaluation of the delivery technologies for poorly water-soluble drugs are proposed.
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An Overview of 3D Printing Technologies for Soft Materials and Potential Opportunities for Lipid-based Drug Delivery Systems.
TL;DR: The future utility of 3DP for printing soft materials, particularly for lipid-based drug delivery systems, offers great advantages and the technology will potentially support patient compliance and drug effectiveness via a personalised medicine approach.
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A tunable Caco-2/HT29-MTX co-culture model mimicking variable permeabilities of the human intestine obtained by an original seeding procedure
Arnaud Béduneau,Camille Tempesta,Stéphane Fimbel,Yann Pellequer,Vincent Jannin,Frédéric Demarne,Alf Lamprecht,Alf Lamprecht +7 more
TL;DR: The HT29-MTX seeding day was a key factor to set up an in vitro intestinal model with tailor-made barrier properties in terms of P-gp expression and paracellular permeability.