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Carine Bécamel
Researcher at University of Montpellier
Publications - 39
Citations - 2176
Carine Bécamel is an academic researcher from University of Montpellier. The author has contributed to research in topics: Receptor & G protein-coupled receptor. The author has an hindex of 21, co-authored 34 publications receiving 1955 citations. Previous affiliations of Carine Bécamel include Centre national de la recherche scientifique & French Institute of Health and Medical Research.
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Journal ArticleDOI
Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation
TL;DR: 5-HT receptors are engaged in pre- or post-synaptic complexes composed of many GPCR-interacting proteins that have been implicated in targeting, trafficking to or from the membrane, desensitization, and fine-tuning of signaling.
Journal Article
Novel brain-specific 5-HT4 receptor splice variants show marked constitutive activity: role of the C-terminal intracellular domain.
TL;DR: The constitutive activity of the new splice variants with short C-terminal sequences was higher than that of the long C-Terminal sequence variants, which may indicate that the short variants have a higher capacity for isomerization from the inactive to the active conformation.
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Synaptic multiprotein complexes associated with 5-HT2C receptors: a proteomic approach
Carine Bécamel,Gérard Alonso,Nathalie Galéotti,Emmanuelle Demey,Patrick Jouin,Christoph Ullmer,Aline Dumuis,Joël Bockaert,Philippe Marin +8 more
TL;DR: 15 proteins that interact with the C‐ terminal tail of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor are identified and shown to be associated with protein networks that are important for its synaptic localization and its coupling to the signalling machinery.
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The Serotonin 5-HT2A and 5-HT2C Receptors Interact with Specific Sets of PDZ Proteins
Carine Bécamel,Sophie Gavarini,Benjamin Chanrion,Gérard Alonso,Nathalie Galéotti,Aline Dumuis,Joël Bockaert,Philippe Marin +7 more
TL;DR: It is shown that residues located at the -1 position and upstream the PDZ ligand in the C terminus of the 5- HT2A and 5-HT2C receptors are major determinants in their interaction with specific PDZ proteins.
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GPCR interacting proteins (GIPs) in the nervous system: Roles in physiology and pathologies.
TL;DR: The role of GIPs is highlighted in some important neurological and psychiatric disorders, as well as their potential for the future development of therapeutic drugs.