C
Carlos Lois
Researcher at California Institute of Technology
Publications - 72
Citations - 13802
Carlos Lois is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Olfactory bulb & Neurogenesis. The author has an hindex of 33, co-authored 69 publications receiving 12395 citations. Previous affiliations of Carlos Lois include Picower Institute for Learning and Memory & University of Massachusetts Medical School.
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Journal ArticleDOI
Long-distance neuronal migration in the adult mammalian brain
TL;DR: Grafted and endogenous SVZ cells in the lateral ventricle of adult mice migrate long distances and differentiate into neurons in the olfactory bulb.
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Germline Transmission and Tissue-Specific Expression of Transgenes Delivered by Lentiviral Vectors
TL;DR: Transgenic mice carrying the green fluorescent protein (GFP) gene driven by a ubiquitously expressing promoter are generated and transgenic rats that express GFP at high levels are generated, suggesting that this technique can be used to produce other transgenic animal species.
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Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes
Manuel Álvarez-Dolado,Ricardo Pardal,José Manuel García-Verdugo,John R. Fike,Hyun O. Lee,Klaus Pfeffer,Carlos Lois,Sean J. Morrison,Arturo Alvarez-Buylla +8 more
TL;DR: Using a simple method based on Cre/lox recombination to detect cell fusion events, it is demonstrated that bone-marrow-derived cells (BMDCs) fuse spontaneously with neural progenitors in vitro, raising the possibility that cell fusion may contribute to the development or maintenance of these key cell types.
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Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia.
TL;DR: This report shows that SVZ cells labeled in the brains of adult mice with [3H]thymidine differentiate directly into neurons and glia in explant cultures, and shows that 98% of the neurons that differentiate from the SVZ explants are derived from precursor cells that underwent their last division in vivo.
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Chain Migration of Neuronal Precursors
TL;DR: Electron microscopic analysis of serial sections showed that during chain migration, neural precursors moved associated with each other and were not guided by radial glial or axonal fibers.