Natural products afford a window of opportunity to study important biology. If the natural product is used or abused by human beings, finding its biological target(s) is all the more significant. Hot pepper is eaten on a daily basis by an estimated one-quarter of the world’s population and

Vanilloid (Capsaicin) Receptors and Mechanisms

Chemical modification of lignins: Towards biobased polymers

/pdf/studies-in-surface-science-and-catalysis-2ogdlcr44y.pdf

Studies in Surface Science and Catalysis

Adsorption kinetic models: Physical meanings, applications, and solving methods.

Towards lignin-based functional materials in a sustainable world

Along more than a decade, R&D on supercritical fluid extraction (SFE) of vegetable matrices has been increasingly reported in the literature. Aiming at portraying the current state of this field and its evolution in terms of raw materials, products, modes of operation, optimization, modeling techniques, and closeness to industrial application, a large compilation of almost 600 essays from 2000 to 2013 has been deeply analyzed in order to unveil those indicators and their trends. Furthermore, strengths and weaknesses are identified, and some remarks that may drive upcoming research are provided. Globally, more than 300 species are reported in the literature, with prevalence of the extraction of seeds (28% of works) and leaves (17%). The main families of extracted compounds, cosolvents and operating conditions adopted are critically examined, being possible to conclude that researchers investigate many times working regions far from the optimum due to practical limitations or absence of experimental optimization. Current phenomenological, statistical and semi-empirical approaches are reviewed, along with scale-up studies, and economic analysis. In the whole, the most comprehensive picture over SFE of vegetable matrices is provided in this review, highlighting pertinent aspects and opportunities that may further consolidate the convincing route of this technology for the next years.

Supercritical fluid extraction of vegetable matrices: Applications, trends and future perspectives of a convincing green technology

Suppression of bladder hyperreflexia by intravesical resiniferatoxin.

The supercritical fluid extraction (SFE) of liquids and solid materials is gaining increasing interest and commercial application in last decades, most particularly under the recent concept of green chemistry and biorefinery. Hence, it is fundamental to provide adequate modeling of the SFE, in order to optimize operating conditions and simulate the global process. This work intends to review the most significant and physically sound models published in the literature for countercurrent liquid-supercritical fluid extraction and SFE of solid matrices, such as the linear driving force, shrinking core, broken and intact cells, and the combination of BIC and shrinking core models. The main assumptions and mass transfer expressions are presented and discussed.

Review of kinetic models for supercritical fluid extraction

Supercritical fluid extraction of grape seed (Vitis vinifera L.) oil. Effect of the operating conditions upon oil composition and antioxidant capacity

Unified approach to the self-diffusion coefficients of dense fluids over wide ranges of temperature and pressure—hard-sphere, square-well, Lennard–Jones and real substances

Carlos M. Silva

Papers

Supercritical fluid extraction of vegetable matrices: Applications, trends and future perspectives of a convincing green technology

Suppression of bladder hyperreflexia by intravesical resiniferatoxin.

Review of kinetic models for supercritical fluid extraction

Supercritical fluid extraction of grape seed (Vitis vinifera L.) oil. Effect of the operating conditions upon oil composition and antioxidant capacity

Unified approach to the self-diffusion coefficients of dense fluids over wide ranges of temperature and pressure—hard-sphere, square-well, Lennard–Jones and real substances