C
Carmen Coombs
Researcher at University of Pittsburgh
Publications - 6
Citations - 2127
Carmen Coombs is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Apoptosis-inducing factor & Emergency department. The author has an hindex of 5, co-authored 5 publications receiving 2023 citations. Previous affiliations of Carmen Coombs include Boston Children's Hospital & University of Washington.
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Journal ArticleDOI
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor.
Seong-Woon Yu,Hongmin Wang,Marc F. Poitras,Carmen Coombs,William J. Bowers,Howard J. Federoff,Guy G. Poirier,Ted M. Dawson,Valina L. Dawson +8 more
TL;DR: It is shown that PARP-1 activation is required for translocation of apoptosis-inducing factor (AIF) from the mitochondria to the nucleus and that AIF is necessary for PARp-1–dependent cell death.
Journal ArticleDOI
Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death.
Hongmin Wang,Seong-Woon Yu,David W. Koh,Jasmine Lew,Carmen Coombs,William J. Bowers,Howard J. Federoff,Guy G. Poirier,Ted M. Dawson,Valina L. Dawson +9 more
TL;DR: It is reported here that apoptosis-inducing factor (AIF) mediates PARP-1-dependent glutamate excitotoxicity in a caspase-independent manner after translocation from the mitochondria to the nucleus.
Journal ArticleDOI
Disparities in osteoporosis screening between at-risk African-American and white women.
Redonda G. Miller,Bimal H. Ashar,Jennifer R. Cohen,Melissa Camp,Carmen Coombs,Elizabeth K. Johnson,Christine R. Schneyer +6 more
TL;DR: A significant disparity in the recommendation for osteoporosis screening for African-American versus white women of similar risk is found, as well as evidence of disparate osteoporeosis prevention and treatment, confirming results of other studies.
Journal ArticleDOI
Design, Implementation, and Evaluation of a Simulation-Based Clinical Correlation Curriculum as an Adjunctive Pedagogy in an Anatomy Course.
Carmen Coombs,Ryan Y. Shields,Ryan Y. Shields,Elizabeth A. Hunt,Ying Wei Lum,Patrick R. Sosnay,Julianne S. Perretta,Rhett H. Lieberman,Nicole Shilkofski +8 more
TL;DR: The design, implementation, and preliminary evaluation of a simulation-based clinical correlation curriculum in an anatomy course for first-year medical students at Perdana University Graduate School of Medicine suggests that using simulation as an adjunctive pedagogy can lead to excellent short-term knowledge retention.
Journal ArticleDOI
Practice Variation and Effects of E-mail-only Performance Feedback on Resource Use in the Emergency Department.
Melissa M. Tavarez,Melissa M. Tavarez,Brandon Ayers,Jong H Jeong,Carmen Coombs,Carmen Coombs,Ann Thompson,Ann Thompson,Robert W. Hickey,Robert W. Hickey +9 more
TL;DR: Performance feedback provided only via e-mail to pediatric emergency physicians on a quarterly basis does not seem to significantly impact management practices for patients with undifferentiated vomiting and/or diarrhea.