Carole N. M. Brouwer

TL;DR: Data do not lend support to the use of pneumococcal conjugate vaccine to prevent otitis media in previously unvaccinated toddlers and children with a history of recurrent AOM.

TL;DR: The OM-6 appears to be the best available instrument to assess functional health status in children with OM in a research setting, however, the lack of true HRQoL instruments as well as incomplete data on their reliability and validity, limit both the current knowledge of HRZoL in OM and the application of current instruments in both research and clinical practice.

TL;DR: The quality of life of 384 Dutch children aged 1–7 years with recurrent acute otitis media is compared with that of children from four reference populations: children from a general population; children with mild‐to‐moderate asthma, children with Mild‐to-moderately severe chronic illness, and US children with persistent or recurrent otitisMedia.

TL;DR: Both generic and disease-specific questionnaires used in this study showed good psychometric qualities and responsiveness for use in clinical studies on children with rAOM and anchor-based methods resulted in similar ranges for the minimally clinical important differences.

TL;DR: Pneumococcal vaccination has no beneficial effect compared with control vaccination on either HRQoL or FHS in children 1 to 7 years old with RAOM.