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Carrie A. Redlich

Researcher at Yale University

Publications -  157
Citations -  5854

Carrie A. Redlich is an academic researcher from Yale University. The author has contributed to research in topics: Occupational asthma & Hexamethylene diisocyanate. The author has an hindex of 38, co-authored 143 publications receiving 5139 citations. Previous affiliations of Carrie A. Redlich include University of Toronto & University of Tennessee Health Science Center.

Papers
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Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation.

TL;DR: The data suggest that, in contrast to CHS, induction of T(H)2 responses after epicutaneous exposure to diisocyanates is strongly genetically influenced, and the lung inflammatory response to inhaled HDI appears to depend primarily on effective generation of these CD4(+) T( H) 2 responses, as is the case in atopic asthma.
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Respiratory Protection from Isocyanate Exposure in the Autobody Repair and Refinishing Industry

TL;DR: It is concluded that negative pressure, air-purifying half-facepiece respirators equipped with organic vapor cartridges and paint prefilters provide effective protection against isocyanate exposure in spray and priming operations if workers are properly trained and fitted.
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Human innate immune responses to hexamethylene diisocyanate (HDI) and HDI–albumin conjugates

TL;DR: Background Isocyanates, a leading cause of occupational asthma, are known to induce adaptive immune responses; however, innate immune responses, which generally precede and regulate adaptive immunity, remain largely uncharacterized.
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Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate

TL;DR: Several of the MDI conjugation sites are not conserved in albumin from other species, and this may suggest species differences in epitope specificity for self protein (albumin)-isocyanate conjugates.