C
Catherine M. Dalton
Researcher at UCL Institute of Neurology
Publications - 45
Citations - 4289
Catherine M. Dalton is an academic researcher from UCL Institute of Neurology. The author has contributed to research in topics: Multiple sclerosis & Clinically isolated syndrome. The author has an hindex of 28, co-authored 43 publications receiving 4118 citations. Previous affiliations of Catherine M. Dalton include Moorfields Eye Hospital & University College London.
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Journal ArticleDOI
A Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis
David Miller,Omar Khan,William A. Sheremata,Lance D Blumhardt,George P.A. Rice,Michele A Libonati,Allison J Willmer-Hulme,Catherine M. Dalton,Katherine A. Miszkiel,Paul O'Connor +9 more
TL;DR: In a placebo-controlled trial, treatment with natalizumab led to fewer inflammatory brain lesions and fewer relapses over a six-month period in patients with relapsing multiple sclerosis.
Journal ArticleDOI
Early development of multiple sclerosis is associated with progressive grey matter atrophy in patients presenting with clinically isolated syndromes.
Catherine M. Dalton,Declan T. Chard,GR Davies,Katherine A. Miszkiel,Daniel R. Altmann,K Fernando,Gordon T. Plant,Alan J. Thompson,David Miller +8 more
TL;DR: It is suggested that progressive grey matter, but not white matter, atrophy is seen in the earliest clinically observable stages of relapse onset multiple sclerosis, and this is only moderately related to lesion accumulation.
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Application of the new McDonald criteria to patients with clinically isolated syndromes suggestive of multiple sclerosis
Catherine M. Dalton,P A Brex,Katherine A. Miszkiel,S. J. Hickman,David G. MacManus,Gordon T. Plant,Alan J. Thompson,David Miller +7 more
TL;DR: Using the new McDonald criteria more than doubled the rate of diagnosis of MS within a year of presentation with a clinically isolated syndrome and the high specificity, positive predictive value, and accuracy of the new criteria for clinically definite MS support their clinical relevance.
Journal ArticleDOI
Management of acute optic neuritis
S. J. Hickman,S. J. Hickman,Catherine M. Dalton,Catherine M. Dalton,DH Miller,Gordon T. Plant +5 more
TL;DR: The condition's association with multiple sclerosis will be considered in the light of studies that define the risk for development of multiple sclerosis and with respect to results of trials of disease-modifying drugs in individuals.
Journal ArticleDOI
Precise estimate of fundamental in-vivo MT parameters in human brain in clinically feasible times
TL;DR: A methodology is presented for extracting precise quantitative MT parameters using a magnetisation-prepared spoiled gradient echo sequence and it is hoped that this new technique will shed light on the properties and dynamics of water compartments within the brain.