C
Catherine McDermott
Researcher at Bond University
Publications - 63
Citations - 5581
Catherine McDermott is an academic researcher from Bond University. The author has contributed to research in topics: Pyocyanin & Acetylcholine. The author has an hindex of 15, co-authored 60 publications receiving 4441 citations. Previous affiliations of Catherine McDermott include University College Cork.
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Journal ArticleDOI
Protection against Radiotherapy-Induced Toxicity.
Susan Hall,Santosh Rudrawar,Matthew Zunk,Nijole Bernaitis,Devinder Arora,Catherine McDermott,Shailendra Anoopkumar-Dukie +6 more
TL;DR: The aim of this review was to evaluate and summarise the evidence that exists for both the known radioprotectant agents and the agents that show promise as future radioprotsection agents.
Journal ArticleDOI
Pyocyanin-induced toxicity in A549 respiratory cells is causally linked to oxidative stress.
Lee S. Gloyne,Gary Grant,Anthony V. Perkins,Katie L. Powell,Catherine McDermott,Peter V. Johnson,Gregory J. Anderson,Milton J. Kiefel,Shailendra Anoopkumar-Dukie +8 more
TL;DR: Parallel measures of ROS production, antioxidant levels and cytotoxicity provide convincing evidence that pyocyanin-induced cytot toxicity in A549 respiratory cells is mediated by acute ROS production and subsequent oxidative stress.
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Effects of pseudomonas aeruginosa virulence factor pyocyanin on human urothelial cell function and viability
Catherine McDermott,Russ Chess-Williams,Gary Grant,Anthony V. Perkins,Amelia J. McFarland,Andrew K. Davey,Shailendra Anoopkumar-Dukie +6 more
TL;DR: The virulence factor depressed stimulated adenosine triphosphate release, which to the authors' knowledge is a novel finding with implications for awareness of bladder filling in patients with P. aeruginosa urinary tract infection.
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Novel insights into the mechanism of cyclophosphamide-induced bladder toxicity: chloroacetaldehyde's contribution to urothelial dysfunction in vitro.
TL;DR: CAA in addition to acrolein contributes to the urotoxicity of cyclophosphamide and ifosfamide, and Alterations in urothelial cell viability and mediator release may be causally linked to oxidative stress, with NAC providing protection against changes.
Journal ArticleDOI
Induction of inflammatory cytokines and alteration of urothelial ATP, acetylcholine and prostaglandin E2 release by doxorubicin
TL;DR: Findings indicate that inflammatory cytokines interleukin-8 and -1β are induced and urothelial mediator release is affected by treatment with doxorubicin at clinically relevant concentrations and durations of treatment.