Cathy Fernandes

TL;DR: It is suggested that both types of plus-maze may be measuring the same type of anxiety with different sensitivities on trial 1 (e.g., generalised anxiety or fear of open spaces); different types of anxiety on trial 2 (without ledges)--phobia/fear of heights; with ledges--not known), and trial 3 in the maze with ledge, yet another type of Anxiety.

TL;DR: It is shown that the PNN protein Brevican is a critical regulator of interneuron plasticity and simultaneously controls cellular and synaptic forms of plasticity in PV+ cells by regulating the localization of potassium channels and AMPA receptors.

TL;DR: The results suggest caution should be exercised in interpreting the results from female rats in tests validated on males because the primary controlling factor may be different.

TL;DR: Evidence from both epidemiological and animal studies indicates that cannabis use during adolescence carries particular risk in addiction, and further studies are warranted given the increase in the concentration of the main active ingredient in street preparations of cannabis and a decreasing age of first-time exposure to cannabis.

TL;DR: The discovery of pathogenic CNVs provide new opportunities for translation leading to patent benefit, including improvements in clinical genetic diagnosis and genetic counselling, the possibility of clinician decision-making tools for risk prediction, and the identification of drug targets and implementation of personalised medicine using stratification by genotype.